PhD - Structural Biology
University of Cambridge, UK - 2008

Sheena D'Arcy
Associate Professor - Chemistry and Biochemistry
Professional Preparation
BS - Biochemistry and Biology
University of Sydney, Australia - 2003
University of Sydney, Australia - 2003
Publications
Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories 2024 - Journal Article
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex 2023 - Journal Article
Molecular basis of RanGTP-activated nucleosome assembly with Histones H2A-H2B bound to Importin-9 2023 - Other
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex 2022 - Other
Hydrogen-deuterium exchange mass spectrometry of Mtr4 with diverse RNAs reveals substrate-dependent dynamics and interfaces in the arch 2022 - Journal Article
News Articles
NIH Grant Enables Chemist To Unwrap DNA Mysteries

D’Arcy’s research focuses on the structure and function of the proteins that are involved in gene transcription — the process of “reading” DNA instructions to create the proteins that carry out life functions.