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Sheena D'Arcy

Sheena D'Arcy

Associate Professor - Chemistry and Biochemistry
 
972-883-2915
BSB12661
D'Arcy Lab
ORCID

Not currently accepting undergraduate students

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Professional Preparation

PhD - Structural Biology
University of Cambridge, UK - 2008
BS - Biochemistry and Biology
University of Sydney, Australia - 2003

Publications

Molecular basis of RanGTP-activated nucleosome assembly with Histones H2A-H2B bound to Importin-9 2023 - Other
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex 2023 - Journal Article
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex 2022 - Other
Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity 2022 - Journal Article
Hydrogen-deuterium exchange mass spectrometry of Mtr4 with diverse RNAs reveals substrate-dependent dynamics and interfaces in the arch 2022 - Journal Article
An activity-based fluorescent sensor for the detection of the phenol sulfotransferase SULT1A1 in living cells 2021 - Journal Article
Hydrogen-deuterium exchange mass spectrometry of Mtr4 with diverse RNAs reveals substrate-dependent dynamics and interfaces in the arch 2021 - Other
Conformational Dynamics Contribute to Substrate Selectivity and Catalysis in Human Kynureninase 2020 - Journal Article

News Articles

NIH Grant Enables Chemist To Unwrap DNA Mysteries
NIH Grant Enables Chemist To Unwrap DNA Mysteries Dr. Sheena D’Arcy, assistant professor of chemistry in the School of Natural Sciences and Mathematics, recently received a Maximizing Investigators’ Research Award for Early Stage Investigators (ESI-MIRA) (grant number R35GM133751) from the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH).

D’Arcy’s research focuses on the structure and function of the proteins that are involved in gene transcription — the process of “reading” DNA instructions to create the proteins that carry out life functions.