Professional Preparation
Postdoc - Pain Neurobiology
UT Dallas - 2017
Postdoc - Hypothalamic Research
UT Southwestern Medical Center - 2015
PhD - Immunophysiology and Behavior
University of Illinois at Urbana-Champaign - 2012
B.S. - Animal Science
University of Illinois at Urbana-Champaign - 2006
Research Areas
Research Interests
Cellular and Molecular Neuroscience. How peripheral stimuli communicate to the CNS to elicit complex behaviors: An emphasis on pain, depression, and metabolism.
Research Statement
Dr. Burton is a new Assistant Professor whose research focuses on how the immune system modulates peripheral sensory neurons to regulate pain and energy homeostasis. Michael received his BS and PhD in Animal Sciences with a focus on Immunophysiology and Behavior at the University of Illinois at Urbana-Champaign. He then moved to Dallas, TX to begin his postdoctoral fellowship work in the Department of Hypothalamic Research at UT Southwestern Medical Center. There Michael gained skills in molecular genetics, neuroendocrinology, and neuroanatomy; in studies that focused on how peripheral ganglia recognized dietary components. He then moved to the UT-Dallas campus to focus on how immune cells influence the transition to chronic pain. It was the fusion of these 2 experiences that formed the basis of a recently awarded NIH-Transition-to-Faculty Award. He believes in order to traverse the gap between basic research and clinical application to the patient, we must realize and appreciate pre-clinical research. He is excited at the notion to play a role in this process, and help humankind through his research in pain development, depression, and metabolic disorders that we deal with every day.
Publications
Sensory Neurons, Neuroimmunity, and Pain Modulation by Sex Hormones 2021 -
Journal Article
Human cells and networks of pain: Transforming pain target identification and therapeutic development 2021 -
Journal Article
Homeostatic Regulation of Estrus Cycle of Young Female Mice on Western Diet 2021 -
Journal Article
The Neuroimmunology of Chronic Pain: From Rodents to Humans 2021 -
Journal Article
TLR4 Signaling Selectively and Directly Promotes CGRP Release from Vagal Afferents in the Mouse 2021 -
Journal Article
Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain 2021 -
Journal Article
Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity 2021 -
Journal Article
The role of cap-dependent translation in aged-related changes in neuroimmunity and affective behaviors 2021 -
Journal Article
The role of microglia versus peripheral macrophages in maladaptive plasticity after nerve injury 2021 -
Journal Article
eIF4E phosphorylation modulates pain and neuroinflammation in the aged 2020 -
Journal Article
Appointments
Assistant Professor
UT Dallas [2017–Present]
Neuroscience Department
Founding Member
Center for Advanced Pain Studies (CAPS) [2019–Present]
CAPS
Affiliate
Center for Vital Longevity [2020–Present]
CVL
Awards
Fellow - African Science Institute [2021]
Certificate of Congressional Recognition - U.S. House of Representatives [2021]
ACT Fellow - American Society for Cell Biology [2020]
Rita Allen Pain Scientist Award - Rita Allen Foundation [2019]
Mitchell Max Award - NIH Pain Consortium [2019]
Keystone Symposia Fellow - Keystone Symposia [2018]
Future Leaders Award - The Endocrine Society [2017]
Future Leader Award - American Pain Society [2017]
News Articles

Two new assistant professors have joined the
School of Behavioral and Brain Sciences (BBS) faculty this fall, and one is a familiar face.
Dr. Michael Burton, added as an assistant professor of neuroscience, has been a postdoctoral researcher at The University of Texas at Dallas since 2015. He joins
Dr. Jiyoung Park, assistant professor of psychology, as new tenure-track professors in BBS this semester.

A postdoctoral researcher in the
School of Behavioral and Brain Sciences has won a prestigious grant from the National Institutes of Health (NIH) that is intended to help him further his research and transition to a faculty position. It is the first time that a postdoc from UT Dallas has won the award.
Dr. Michael Burton, who works in the
neuroscience department with associate professor
Dr. Ted Price, will receive approximately $800,000 for winning a K22 grant from the National Institute of Neurological Disorders and Stroke (NINDS). The grant will provide funds for Burton’s research on how the immune system can affect pain.
Dr. Michael Burton, an assistant professor in the
School of Behavioral and Brain Sciences, has received the 2019
Mitchell Max Award for Research Excellence from the National Institutes of Health
Pain Consortium.
Burton was selected for his presentation on delayed-onset neuropathic pain in older men. His research suggests that immune system hyperactivity at an advanced age can trigger hyperexcitability in neurons that can produce chronic pain long after an injury.
Scientists in The University of Texas at Dallas’
Center for Advanced Pain Studies (CAPS) have furthered the understanding of how chronic pain functions differently in males and females, including identifying different ways pain begins at the cellular level.
Researchers from the
Department of Neuroscience in the
School of Behavioral and Brain Sciences (BBS) teamed up with colleagues from Sweden’s Karolinska Institute on two studies published
Aug. 5 and
Sept. 16 in the journal
Pain. Their work builds upon
earlier studies from CAPS faculty regarding sex dimorphisms — differences between the sexes.
“As recently as 2014, laboratories were using only males to analyze what was happening, and that led to failures in clinical and preclinical trials,” said
Dr. Michael Burton, assistant professor of neuroscience and co-senior author of both papers. “It was apparent that something was missing from the equation.
Activities
Scientific Advisory Board Member/ Keystone Fellowship
Advisory Board Member
LSAMP Bridge-to-Doctorate Program
Advisory Board Member
Mentoring Institute for Neuroscience Diversity Scientists (MINDS)
Affiliations
Associate Chair, Basic Science Advisory Group (BSAG), Endocrine Society
2019/01
Board Member, Project ACCESS, Alliance to Catalyze Change for Equity in STEM Success,
2020/07
Associate Editor, Frontiers in Immunology, Molecular Innate Immunity. Guest Editor of Neural control of Immunity, Frontiers,
2020/03–2021/12
Associate Review Editor, Frontiers in Pain Research, Pharmacological Treatment of Pain, Frontiers,
2021/06
Editorial Board Member, Journal of Neuroinflammation
2021/02
Deputy Editor, Neurobiology of Pain
2021/08