J. Liu, M. Yu, C. Zhou, S. Yang, X. Ning, and J. Zheng, Passive Tumor Targeting of Renal Clearable Luminescent Gold Nanoparticles: Long Tumor Retention and Fast Normal Tissue Clearance, J. Am. Chem. Soc., 2013, 135(13), 4978-4981. (Featured in JACS Spotlights) 2013 - Publication
J.B. Liu, M.X. Yu, C. Zhou, and J. Zheng, "Renal Clearable Inorganic Nanoparticles: A New Frontier of Bionanotechnology", Mater. Today, 2013, accepted. 2013 - Publication
C. Zhou, S. Yang, J. Liu, M. Yu, and J. Zheng, Luminescent Gold Nanoparticles: A New Class of Nanoprobes for Biomedical Imaging, Exp. Bio. Med., 2013, accepted. 2013 - Publication
J.B. Liu, M.X. Yu, X. Ning, C. Zhou, S.Y. Yang, and J. Zheng, "PEGylation and Zwitterionization: Pros and Cons in Renal Clearance and Tumor Targeting of Near-IR-Emitting Gold Nanoparticles", Angew. Chem. Int. Ed., 2013, DOI:10.1002/anie.201304465. (Highlighted as VIP) 2013 - Publication
C. Zhou, G. Hao, T. Patrick, J. Liu, M. Yu, S. Sun, O. Oz, X. Sun, and J. Zheng, “Near Infrared Emitting Radioactive Gold Nanoparticles with Small-molecule-like Pharmacokinetics”, Angew. Chem. Int. Ed., 2012, DOI: 10.1002/anie.201203031. 2012 - Publication
C. Zhou, J. Yu, Y. Qin, and J. Zheng, “Grain Size Effects in Polycrystalline Gold Nanoparticles”, Nanoscale, 2012, 4(14), 4228-4233. (Highlighted as the inside front cover) 2012 - Publication
J. Zheng, C. Zhou, M. Yu, J. Liu, Different Sized Luminescent Gold Nanoparticles, Nanoscale, 2012, 4(14), 4073-4083. (Citation: 30) 2012 - Publication
J. Zheng, C. Zhou, M. Yu, J. Liu, “Different Sized Luminescent Gold Nanoparticles”, Nanoscale, 2012, 4(14), 4073-4083. 2012 - Publication
S. Yang, C. Zhou, J. Liu, M. Yu, and J. Zheng, “One-step Interfacial Synthesis and Assembly of Fluorescent Ultrathin Au@Silica Membrane”, Adv. Mater., 2012, 24(24), 3218-3222. (Highlighted by Materials 360) 2012 - Publication
A. Rahy, C. Zhou, J. Zheng, S. Y. Park, M. Kim, I. Jang, S. J. Cho, and D. J. Yang, “Photoluminescent Carbon Nanoparticles Produced by Confined Combustion of Aromatic Compounds”, Carbon, 2012, 50(3), 1298-1302. 2012 - Publication
UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.Dr. Jie Zheng
, associate professor of chemistry and biochemistry at UT Dallas, and his colleagues have combined tiny gold nanoparticles with a technique called in vivo near-infrared fluorescence imaging to study early stage kidney disease in a live animal model.
Dr. Jie Zheng, a member of the chemistry faculty at UT Dallas, has received more than $1.2 million in funding from the Cancer Prevention and Research Institute of Texas (CPRIT) for work on safer nanoparticles that can adhere to prostate tumor cells, making earlier diagnosis possible.
Dr. Zheng, assistant professor of chemistry, explores biomedical applications of tiny gold nanoparticles that respond to the acidic microenvironments of prostate tumors. When introduced in the body, the particles can take advantages of a slight difference in pH between the tumors and normal tissue, essentially lighting up cancer cells to which they adhere, making them easier to detect with a variety of medical imaging tools.
Dr. Jie Zheng
believes he’s turned a barrier into a bridge when it comes to nanomedicine implementation.
The professor of chemistry and his research team at The University of Texas at Dallas have demonstrated that nanomedicines can be designed to interface with a natural detoxification process in the liver to improve their disease targeting while minimizing potential side effects.
, published July 15 in Nature Nanotechnology
, indicates a path to making nanomedicine safer and more efficient.
Accolades is an occasional News Center feature that highlights recent accomplishments of The University of Texas at Dallas faculty and students. To submit items for consideration, contact your school’s communications manager
Dr. Jie Zheng
, professor of chemistry
, has been elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). He is among 156 new fellows announced March 24.
Zheng was elected for “his outstanding contributions to fundamental understandings of in vivo nanoparticle transport and the development of renal clearable nanomedicines,” according to the institute.