Jie Zheng

Ph.D. - Department of Chemistry and Biochemistry
Georgia Institute of Technology - 2005

B.S. - Department of Chemistry
Inner Mongolia University - 1994

Nanoparticle Transport in Proximal Tubules with Rhabdomyolysis‐Induced Necrosis 2024 - Journal Article

Gold Nanoparticle Transport in the Injured Kidneys with Elevated Renal Function Biomarkers 2024 - Journal Article

Physiological principles underlying the kidney targeting of renal nanomedicines 2024 - Journal Article

Proximal tubules eliminate endocytosed gold nanoparticles through an organelle-extrusion-mediated self-renewal mechanism 2023 - Journal Article

Crosstalk between Hepatic Glutathione Efflux and Tumor Targeting Efficiency of Indocyanine Green‐Conjugated Gold Nanoparticles 2023 - Journal Article

Noninvasive monitoring of hepatic glutathione depletion through fluorescence imaging and blood testing 2021 - Journal Article

Salivary Excretion of Renal‐Clearable Silver Nanoparticles 2020 - Journal Article

Tailoring Kidney Transport of Organic Dyes with Low-Molecular-Weight PEGylation 2020 - Journal Article

Postdoctoral Fellow
Harvard University [2005–2008]

Research Assistant
Georgia Institute of Technology [2002–2005]

Material Research Society spring conference(Invited talk)

2005–2005 J. Zheng, R.M. Dickson, Material Research Society spring conference, San Francisco, CA , March, 2005 (Invited talk)

Honors and Awards

• Honored for individual accomplishment, College of Science, Georgia Tech. 4/2005
• Material Research Society Graduate Student Award 3/2005
• House-Flashka-Ashby graduate student award, Georgia Tech. 10/2004

Patents

1.  X.W.Zhuang, J. Zheng, "GRANULAR NANOPARTICLES HAVING BRIGHT FLUORESCENCE AND GIANT RAMAN ENHANCEMENTS " Patent applied for, 2008
2.  R.M. Dickson, J. Zheng, "Nano-sized optical fluorescence labels and uses thereof", Patent issued WO2004003558 (licensed by Invitrogen), 2005
3.  Z.N. Bao, J. Zheng, "Fom1ing closely spaced electrodes", Patent issued, US2005014357, 2005

Technique May Improve Understanding, Detection of Kidney Disease

UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

Dr. Jie Zheng, associate professor of chemistry and biochemistry at UT Dallas, and his colleagues have combined tiny gold nanoparticles with a technique called in vivo near-infrared fluorescence imaging to study early stage kidney disease in a live animal model.

Nanoparticle Study Attracts State Cancer Research Funds

Dr. Jie Zheng, a member of the chemistry faculty at UT Dallas, has received more than $1.2 million in funding from the Cancer Prevention and Research Institute of Texas (CPRIT) for work on safer nanoparticles that can adhere to prostate tumor cells, making earlier diagnosis possible.

Dr. Zheng, assistant professor of chemistry, explores biomedical applications of tiny gold nanoparticles that respond to the acidic microenvironments of prostate tumors. When introduced in the body, the particles can take advantages of a slight difference in pH between the tumors and normal tissue, essentially lighting up cancer cells to which they adhere, making them easier to detect with a variety of medical imaging tools.

Chemists Close Gap in Making Nanomedicines Safer, More Efficient

Dr. Jie Zheng believes he’s turned a barrier into a bridge when it comes to nanomedicine implementation.

The professor of chemistry and his research team at The University of Texas at Dallas have demonstrated that nanomedicines can be designed to interface with a natural detoxification process in the liver to improve their disease targeting while minimizing potential side effects.

Their study, published July 15 in Nature Nanotechnology, indicates a path to making nanomedicine safer and more efficient.

Accolades: Chemist Receives AIMBE Honor; UTD Earns Gold for Sustainability

Accolades is an occasional News Center feature that highlights recent accomplishments of The University of Texas at Dallas faculty and students. To submit items for consideration, contact your school’s communications manager.

Dr. Jie Zheng, professor of chemistry, has been elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). He is among 156 new fellows announced March 24.

Zheng was elected for “his outstanding contributions to fundamental understandings of in vivo nanoparticle transport and the development of renal clearable nanomedicines,” according to the institute.

Dr. Jie Zheng Receives Nearly $1.5 Million from NIH

The National Institutes of Health awarded Dr. Jie Zheng $1,451,573 for his research on Noninvasive Monitoring of Hepatic Glutathione Depletion through Blood Test. The project focuses on the use of gold nanoparticles to detect acute liver damage early through simple blood tests. Dr. Zheng’s groundbreaking research could replace current methods that are more invasive for monitoring and diagnosing liver disease.