Bachelor of Science - Mathematics
Georgetown University
Nikki Delk
Assistant Professor - Biological Sciences
Professional Preparation
Doctor of Philosophy - Molecular Biology
Rice University
Rice University
Research Areas
Inflammation-mediated breast and prostate cancer cell survival and treatment resistance mechanisms, including autophagy and Sequestome-1 functionsPublications
IL-1 induces p62/SQSTM1 and autophagy in ERα+/PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα−/PR− BCa-like phenotype 2018 - Journal Article
Identification of an IL-1-induced gene expression pattern in AR+PCa cells that mimics the molecular phenotype of AR−PCa cells 2018 - Journal Article
IL-1β induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells 2014 - Journal Article
P62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines 2014 - Journal Article
Calmodulin-related CML24 interacts with ATG4b and affects autophagy progression in Arabidopsis 2013 - Journal Article
Interleukin-6: A bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells 2012 - Journal Article
The in vivo performance of plasmonic nanobubbles as cell theranostic agents in zebrafish hosting prostate cancer xenografts 2010 - Journal Article
Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation 2009 - Journal Article
Appointments
Assistant Professor
University of Texas at Dallas [2014–Present]
University of Texas at Dallas [2014–Present]
Faculty Fellow
Rice University [2011–2014]
Rice University [2011–2014]
Postdoctoral Fellow
MD Anderson Cancer Center [2006–2009]
MD Anderson Cancer Center [2006–2009]
Awards
Fellow, Cecil H. and Ida Green Professor in Systems Biology Science - University of Texas at Dallas [2018]
Mentored Research Scientist Career Development Award - NIH [2012]
George J. Schroepfer Jr. Outstanding Ph.D. Thesis in Biochemistry and Cell Biology - Rice University [2006]
Affiliations
Adjunct Professor
2015/07Department of BioSciences, Rice University