Bachelor of Science - Mathematics
Georgetown University
Nikki Delk
Associate Professor - Biological Sciences
972-883-2581
FO3704E
Delk Lab UT Dallas (Facebook)
delklab_utd (Instagram)
Website
ORCID
Not currently accepting undergraduate students
Professional Preparation
Doctor of Philosophy - Molecular Biology
Rice University
Rice University
Research Areas
Inflammation-mediated breast and prostate cancer cell survival and treatment resistance mechanisms, including autophagy and Sequestome-1 functionsPublications
Chronic IL-1-Exposed LNCaP Cells Evolve High Basal p62-KEAP1 Complex Accumulation and NRF2/KEAP1-Dependent and -Independent Hypersensitive Nutrient Deprivation Response 2025 - Journal Article
A microphysiological system reveals neutrophil contact-dependent attenuation of pancreatic tumor progression by CXCR2 inhibition-based immunotherapy. 2024 - Journal Article
Interleukin-1 and Nuclear Factor Kappa B Signaling Promote Breast Cancer Progression and Treatment Resistance 2022 - Journal Article
Chronic IL-1 Exposed AR+ PCa Cell Lines Show Conserved Loss of IL-1 Sensitivity and Evolve Both Conserved and Unique Differential Gene Expression Profiles. 2021 - Journal Article
Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence. 2020 - Journal Article
IL-1-conferred gene expression pattern in ERα+ BCa and AR+ PCa cells is intrinsic to ERα- BCa and AR- PCa cells and promotes cell survival. 2020 - Journal Article
NF-κB signaling promotes castration-resistant prostate cancer initiation and progression. 2020 - Journal Article
IL‐1 induces p62/SQSTM1 and autophagy in ERα+/PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα−/PR− BCa‐like phenotype 2019 - Journal Article
Awards
Fellow, Cecil H. and Ida Green Professor in Systems Biology Science - University of Texas at Dallas [2018]
Mentored Research Scientist Career Development Award - NIH [2012]
George J. Schroepfer Jr. Outstanding Ph.D. Thesis in Biochemistry and Cell Biology - Rice University [2006]
Appointments
Assistant VP for Research Development
Office of Research and Innovation, University of Texas at Dallas [2022–Present]
Office of Research and Innovation, University of Texas at Dallas [2022–Present]
Associate Professor
Biological Sciences Department, University of Texas at Dallas [2020–Present]
Biological Sciences Department, University of Texas at Dallas [2020–Present]
Assistant Professor
Biological Sciences Department, University of Texas at Dallas [2014–2020]
Biological Sciences Department, University of Texas at Dallas [2014–2020]
Faculty Fellow
Department of Biochemistry and Cell Biology, Rice University [2011–2014]
Department of Biochemistry and Cell Biology, Rice University [2011–2014]
Postdoctoral Fellow
Department of Biochemistry and Cell Biology, Rice University [2009–2011]
Department of Biochemistry and Cell Biology, Rice University [2009–2011]
Postdoctoral Fellow
Department of Experimental Radiation Oncology, MD Anderson Cancer Center [2006–2009]
Department of Experimental Radiation Oncology, MD Anderson Cancer Center [2006–2009]
Presentations
News Articles
Affiliations
Adjunct Professor
2015/07–2024/06Department of BioSciences, Rice University