Nikki Delk

Associate Professor - Biological Sciences
Tags: Molecular Biology Cell Biology Cancer Metabolism Cancer Genomics

Professional Preparation

Bachelor of Science - Mathematics
Georgetown University
Doctor of Philosophy - Molecular Biology
Rice University

Research Areas

Inflammation-mediated breast and prostate cancer cell survival and treatment resistance mechanisms, including autophagy and Sequestome-1 functions

Publications

IL-1-conferred gene expression pattern in ERα+ BCa and AR+ PCa cells is intrinsic to ERα- BCa and AR- PCa cells and promotes cell survival. 2020 - Journal Article
NF-κB signaling promotes castration-resistant prostate cancer initiation and progression. 2020 - Journal Article
RELA is sufficient to mediate interleukin‐1 repression of androgen receptor expression and activity in an LNCaP disease progression model 2019 - Journal Article
IL-1 induces p62/SQSTM1 and autophagy in ERα+/PR+ BCa cell lines concomitant with ERα and PR repression, conferring an ERα−/PR− BCa-like phenotype 2018 - Journal Article
Identification of an IL-1-induced gene expression pattern in AR+PCa cells that mimics the molecular phenotype of AR−PCa cells 2018 - Journal Article
HyStem®, a customisable hyaluronan-based hydrogel matrix for 3D cell culture 2017 - Book Chapter
Neuronal Trans-Differentiation in Prostate Cancer Cells 2016 - Journal Article
IL-1β induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells 2014 - Journal Article
P62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines 2014 - Journal Article
Calmodulin-related CML24 interacts with ATG4b and affects autophagy progression in Arabidopsis 2013 - Journal Article

Appointments

Assistant Professor
University of Texas at Dallas [2014–Present]
Faculty Fellow
Rice University [2011–2014]
Postdoctoral Fellow
MD Anderson Cancer Center [2006–2009]

Awards

Fellow, Cecil H. and Ida Green Professor in Systems Biology Science - University of Texas at Dallas [2018]
Mentored Research Scientist Career Development Award - NIH [2012]
George J. Schroepfer Jr. Outstanding Ph.D. Thesis in Biochemistry and Cell Biology - Rice University [2006]

Affiliations

Adjunct Professor
2015/07
Department of BioSciences, Rice University