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Nicholas Dillon

Nicholas Dillon

Assistant Professor - Biological Sciences
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Professional Preparation

Postdoctoral training - Host-Pathogen interactions
University of California- San Diego - 2021
Ph.D. - Microbiology
University of Minnesota - Twin Cities - 2017
M.S. - Biology
University of Minnesota - Twin Cities - 2011
B.S. - Biochemistry
University of Wisconsin- Madison - 2005

Research Areas

Antibiotic Resistance
Since the 1928 discovery of penicillin, the antibiotic era revolutionized the practice of modern medicine, decreasing morbidity and mortality the world over. Unfortunately, rapid evolution of antibiotic resistance (AR), combined with a failing drug discovery pipeline, threatens a post-antibiotic era in which common bacterial infections are once again fatal. The goals of the Dillon lab are therefore to identify, assess, and mechanistically understand antibiotic interactions to design new therapeutical regimens for leading AR bacterial pathogens. We focus on targeting AR pathogens through uncovering novel synergistic antibiotic interactions, understanding the genetic basis for AR, and developing therapies to counter the evolution of AR. We utilize in vitro, ex vivo, and in vivo models of infection to study AR.

Publications

A Clinically Silent Resistance Phenotype That Promotes Acinetobacter baumannii Survival During Colistin Therapy 2026 - Other
Azithromycin robustly synergizes with tetracyclines to overcome acquired minocycline resistance in Acinetobacter baumannii 2026 - Other
Oxidative stress drives potent bactericidal activity of pyrazinamide against Mycobacterium tuberculosis 2025 - Journal Article
Complete genome sequence of pathogenic Pseudomonas aeruginosa strain P4 associated with persistent lung infections 2025 - Journal Article
Complete genome sequence of pathogenic Pseudomonas aeruginosa strain P4 associated with persistent lung infections 2025 - Journal Article
CCL28 modulates neutrophil responses during infection with mucosal pathogens 2024 - Journal Article
Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant Acinetobacter baumannii 2024 - Journal Article
Siderophores mediate antibiotic resistance 2024 - Journal Article

Awards

ASM Peggy Cotter Award - ASM [2025]
ASM Peggy Cotter Award - ASM [2024]
2021 Royal Society of Chemistry's Organic Division Horizon Prize: Robert Robinson Award in Synthetic Organic Chemistry - Royal Society of Chemistry [2021]
Ruth L. Kirschstein Postdoctoral Fellowship in Developing Pediatric Clinical Pharmacology for the Advancement of Therapeutics - NIH [2020]

News Articles

Meet the Newest Group of Tenured, Tenure-Track Faculty at UT Dallas
The University of Texas at Dallas welcomed 25 new tenured and tenure-track faculty members in 2021, with many of them joining the University this fall.
Researchers Receive Trauma Care Grants from UT System
Four University of Texas at Dallas research projects recently received grants totaling nearly $750,000 from the Trauma Research and Combat Casualty Care Collaborative (TRC4), an initiative of the UT System that funds groundbreaking trauma research and product development across its institutions.

Affiliations

Review Editor
2021/01
Frontiers in Molecular Medicine 
Assistant Professor
2021/08
University of Texas at Dallas- Department of Biological Sciences