John Hart, Jr.

Distinguished Chair in Neuroscience
Professor - Behavioral and Brain Sciences
Professor of Neurology, Psychiatry, and Clinical Psychology (UTSW)
Tags: Cognition and Neuroscience

Professional Preparation

University of Maryland School of Medicine - 1983
B.A. - Psychology
The Johns Hopkins University - 1979

Research Areas

Research Interests

My research interests have focused on the neural basis of semantic memory in the human brain. My work, spanning several decades, has focused on identifying the organization of semantic memory in the human brain by proposing that there is both a categorical and featural structure to object memory that exists in multiple memory systems in the brain. My laboratory's recent studies have used functional neuroimaging and electrophysiological investigations to explore the neural mechanisms underlying combining these components of an object together to form an integrated object memory. They recently reported that one neural mechanism by which object recall can occur is via synchronizing gamma brain rhythms that are modulated by the thalamus and proposed the Neural Hybrid Model of Semantic Memory. I am now investigating object memory and word finding deficits in multiple disease states in terms of both diagnosing and designing treatment options based on this model.


Krauss, G.L., Fisher, R., Plate, C., Hart, J., Uematsu, S., Gordon, B, & Lesser, R.P. Cognitive effects of resecting basal temporal language areas. Epilepsia, 37 (5): 476-483, 1996. 1996 - Publication
Small, S. L., Hart, J., Nguyen, T., & Gordon, B. Distributed representations of semantic knowledge in the brain: Computational experiments using feature based codes. In J. A. Reggia, E. Ruppin, & R.S. Berndt (Eds.), Neural Modeling of Brain and Cognitive Disorders, Singapore: World Scientific, 1996. 1996 - Publication
Boatman, D., Miglioretti, D.L., Hart, J., Lamberti, N., Rothlisberger, B., & Gordon, B. Localization and variability in the cortical representation of auditory syllable discrimination and comprehension. Brain and Language, 55:150-152, 1996. 1996 - Publication
Gordon B, Hart J Jr, Lesser RP, & Arroyo S. Mapping cerebral sites for emotion and emotional expression with direct cortical electrical stimulation and seizure discharges. Prog Brain Res, 107:617-22, 1996. 1996 - Publication
Small, S., Hart, J., Nguyen, T., & Gordon, B. Distributed representations of semantic knowledge in the brain. Brain, 118: 441-453, 1995. 1995 - Publication
Small, S., Holland, A.L., Hart, J., Forbes, M.M., & Gordon, B. Response variability in picture naming: A computational study. Clinical Aphasiology, 23: 25-38, 1995. 1995 - Publication
Gordon, B., Hart, J., Boatman, D., Crone, N., Nathan, S., Uematsu, S., Holcomb, H., Krauss, G., Selnes, O.A., & Lesser, R.P. Language and brain organization from the perspectives of cortical electrical interference, direct cortical recording, PET scanning, and acute lesion studies. In D.C. Gajdusek & G.M. McKhann (Eds.), Evolution and Neurology of Language, Vol. X, No. 1 & 2, Elsevier: New York, 1994. 1994 - Publication
Arroyo, S., Lesser, R.P., Fisher, R.S., Vining, E.P., Krauss, G.L., Bandeen-Roche, K., Hart, J., Gordon, B., Uematsu, S., & Webber, R. Clinical and electroencephalographic evidence for sites of origin of seizures with diffuse electrodecremental pattern. Epilepsia, 35: 974-987, 1994. 1994 - Publication
Lesser, R.P., Arroyo, S., Hart, J., & Gordon, B. The use of subdural electrodes for the study of language functions. In A. Kertesz (Ed.), Localization and Neuroimaging in Neuropsychology, Academic Press: San Diego, 1994. 1994 - Publication
Arroyo, S., Lesser, R.P., Gordon, B., Uematsu, S., Hart, J., Schwerdt, P., Andreasson, K., & Fisher, R.S. Mirth, laughter, and gelastic seizures. Brain, 116: 757-780, 1993. 1993 - Publication


University of Texas at Dallas [2006–Present]
Medical Science Director
University of Texas at Dallas [2005–Present]
Professor/ Jane and Bud Smith Distinguished Chair/Cecil Green Chair in Systems Biology
University of Texas at Dallas [2005–Present]

University of Texas at Dallas [2005–Present]
University of Texas Southwestern Medical Center [2005–Present]
Associate Director
GRECC of CAVHS [2004–2005]
Associate Professor
University of Arkansas for Medical Sciences [2003–2005]
Physician Researcher
GRECC, CAVHS [2002–2005]
Geriatric Memory Disorders Clinic, CAVHS [2002–2005]
Staff Physician
Central Arkansas Veterans Healthcare System [2002–2005]


A distinct form of thalamic aphasia due to a semantic feature-Binding deficit.
2002–2002 Segal, J.B., Moo, L., Kraut, M., Hart, J. Cognitive Neuroscience Society, March, 2002.
Cortical rhythms during semantic object recall in Mild Cognitive Impairment
2006–2006 Hart, J,Li, J, Pitcock, J, Calhoun, V, Kraut, M American Academy of Neurology, April, 4, 2006.
Neural hybrid model of semantic object recall.
2004–2004 Hart, J International Neuropsychological Association and Australian Society for the Study of Brain Impairment, Brisbane, Australia, 2004. (Brain Impairment 2004; 5: 27).
Thalamocortical evidence for a constructive memory framework.
2003–2003 Slotnick, S. & Hart, J Society for Neuroscience, 2003.
Absence of anterior cingulate activation in schizophrenic individuals during a semantic feature-binding task.
2004–2004 Rivkin, P., Yassa, M, Hart, J, Kraut, M, Kanaan, R., Calhoun, V, & Pearlson, G. Society of Biological Psychiatry, 2004.

Additional Information

  • Behavioral Neurology and Neuropsychiatry, UCNS, 10/23/06
Editorial Activities
  • 1998-                Editorial Board, Neurocase
  • 2006-2009       Editorial Board, Neuropsychology
  • 2007-                Editorial Board, Journal of Innovative Optical Health Sciences
  • 2009-                Editorial Board, World Journal of Radiology
  • 2010-                Review Editorial Board, Frontiers in Neuropsychiatric Imaging and Stimulation
Medical Licensure
  • Maryland D46185 (exp. 9/30/2012); Arkansas E-3591 (exp. 5/31/11); TX NO583 (exp.11/30/2011) ; DEA BH 412 0870 (10/31/2012); MD CDS M38304 (exp. 4/30/2012) ;  TX TCSRC F0152446 (exp. 4/30/2011)   

News Articles

Neuroscientists Use Magnetic Stimulation to Amplify PTSD Therapy
Researchers from The University of Texas at Dallas have found that a standard therapy for post-traumatic stress disorder (PTSD) is more effective when paired with transcranial magnetic stimulation of the brain.

Dr. John Hart Jr., Dr. Michael Motes and a team of researchers examined whether the effectiveness of cognitive processing therapy (CPT) in treating PTSD could be boosted by adding repetitive transcranial magnetic stimulation (rTMS) just prior to the CPT sessions.
Study Finds Cognitive Impairment in Some Retired NFL Players
A study led by the UT Dallas Center for BrainHealth examining the neuropsychological status of former National Football League players has found heightened incidence of cognitive deficits and depression among retired players.

But researchers from the center and from UT Southwestern Medical Center say their study, published online Monday in JAMA Neurology, also is significant for what it did not find: evidence of cognitive impairment in the majority of ex-players.
New BrainHealth Test May Detect Who Is Most at Risk for Alzheimer's

Researchers at Center for BrainHealth at UT Dallas have developed a test that may help detect who is at risk for Alzheimer’s disease. 

In a study published in the Journal ofAlzheimer’s Disease, scientists found that individuals with amnestic mild cognitive impairment (aMCI) have twice the risk of others in their age group of progressing to Alzheimer’s after identifying a specific variation in their brain waves. 

PTSD Researchers Win Nearly $7.4M Department of Defense Grant
A University of Texas at Dallas neuroscience research team led by Dr. John Hart Jr. has received a nearly $7.4 million grant from the U.S. Department of Defense for a multisite study on a novel treatment protocol for post-traumatic stress disorder (PTSD).
The researchers are seeking up to 330 military veterans with combat-related PTSD for the study, which will include both repetitive transcranial magnetic stimulation (rTMS) and cognitive processing therapy (CPT). The funding comes four months after publication of the team’s Journal of Affective Disorders study, which indicated that CPT for PTSD is more effective when paired with rTMS.


Medical students supervised
1997-99 W. Leo Sugrue
Residents supervised for senior research tutorial
1996-97 Ellen Deibert, M.D. 1998-99 Lauren Moo, M.D., Isaac Silverman, M.D.
Fellows Trained
1999-2001 Lauren Moo, M.D. 1999-2001 Scott Slotnick, Ph.D. 2004-2005 Juan Li, Ph.D. 2006 Richard King, M.D., Ph.D. 2006- Jacque Gamino, Ph.D. 2007-Gail Tillman, Ph.D. 2008-Raksha Anand, Ph.D. 2008-Elizabeth Kanter Bartz, Ph.D. Graduate student supervisors 2006-2008 Raksha Anand 2006-2007 Peter Fauver 2007-2009 Khamid Bhadikirov 2009-2010 Leonardo Estevez 2009- H-S Chiang 2010- Jeremy Strain 2010- Neena Rao
Undergraduate degree students supervised
1999-2000 Felix Yu 1997-99 Tifiini Smith 1996 Lauren Roginski 2006-10 Matthew Brier 2009-10 Shehznan Baqui 2009-10 Nistha Jajal 2009-10 Michael Lugo 2008-10 Rajen Patel