Katherine Damme

PhD - Psychology: Brain, Behavior, and Cognition
Northwestern University - 2018

MS - Psychology
Northwestern University - 2015

BA - Psychology: Research Focus in Cognitive Neuroscience
Vanderbilt University - 2009

Managing clinical heterogeneity in psychopathology: Perspectives from brain research. 2024 - Journal Article

Motor precision deficits in clinical high risk for psychosis 2024 - Journal Article

Physical and mental health in adolescence: novel insights from a transdiagnostic examination of FitBit data in the ABCD study 2024 - Journal Article

A Developmental Perspective on Early and Current Motor Abnormalities and Psychotic-Like Symptoms 2024 - Journal Article

Physical and mental health in adolescence: Novel insights from a transdiagnostic examination of FitBit data in the ABCD Study 2024 - publications

The impact of menarche on hippocampal mechanisms of severity of psychotic-like experiences in the ABCD study. 2024 - publications

Reduced hippocampal volume unmasks distinct impacts of cumulative adverse childhood events (ACEs) on Psychotic-like experiences in late childhood and early adolescence. 2024 - publications

Physical and Mental Health in Adolescence: Novel Insights from a transdiagnostic examination of FitBit data in the ABCD Study 2023 - Other

Assistant Professor
University of Texas -Dallas [2024–Present]

Post-doctoral Research Fellow
Institute for Innovation in Developmental Sciences, Northwestern University [2021–2024]
NIMH Mental Health, Earlier T32 Postdoc Training Program

Postdoctoral Research Fellow
Psychology Department, Northwestern University [2018–2020]
Adolescent Development and Preventative Treatments Lab

Center for Vital Longevity

2024/08
External Fellow

Society for Biological Psychiatry

2022/08
Committee Member

Estrogen and Mechanisms of Psychotic-like Experiences in the Transition to Adolescence

- National Institutes of Mental Health [2024/08–2026/07]

The proposed analyses will leverage the strengths of the ABCD study, capturing this rich variability in estrogen in late childhood and early coupled with critical neural, cognitive, and symptom longitudinally within biological females. This rich dataset will allow us to examine estrogen comprehensively within biological females and whether there is sex specificity to the impact of estrogen levels on PLEs by examining biological males for whom estrogen levels are available. Although not everyone with PLEs will transition to psychosis, these symptoms do reflect underlying psychosis vulnerability in the premorbid period, and tracking changes in PLE levels in the premorbid period may be informative in the early mechanism that may modulate vulnerability related to formal psychotic disorders as a function of adolescent development. Understanding the mechanisms of these estrogen effects within their developmental context will provide insights into how (structural, functional, cognitive, direct clinical impact), when (timing/developmental context), where (hippocampal subvolume), and for whom (sex-specificity) to target intervention to reduce or delay the transition to psychosis.