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Crystal Engineer

Crystal Engineer

Assistant Professor

Research Interests: Auditory processing in neurodevelopmental disorders and plasticity-based therapies to improve neural responses and behavioral outcomes

 
972-883-7246
BSB 14.562
Engineer Lab
Curriculum Vitae
ORCID

Currently accepting graduate students

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Professional Preparation

PhD - Cognition and Neuroscience
University of Texas at Dallas - 2008
MS - Applied Cognition and Neuroscience
University of Texas at Dallas - 2005
BS - Neuroscience
University of Texas at Dallas - 2003

Research Areas

Plasticity
Rodent models of neurodevelopmental disorders
Neuromodulation
Vagus nerve stimulation
Autism
Rett syndrome
Speech
Auditory cortex

Publications

Vagus nerve stimulation rescues impaired fear extinction and social interaction in a rat model of autism spectrum disorder. 2025 - Journal Article
Bursts of vagus nerve stimulation paired with auditory rehabilitation fail to improve speech sound perception in rats with hearing loss. 2024 - Journal Article
Vagus nerve stimulation during training fails to improve learning in healthy rats. 2024 - Journal Article
Pairing tones with vagus nerve stimulation improves brain stem responses to speech in the valproic acid model of autism 2024 - Journal Article
Degraded inferior colliculus responses to complex sounds in prenatally exposed VPA rats. 2024 - Journal Article
Behavioral Paradigm for the Evaluation of Stimulation-Evoked Somatosensory Perception Thresholds in Rats 2023 - Other
Precise sound characteristics drive plasticity in the primary auditory cortex with VNS-sound pairing. 2023 - Journal Article
Behavioral paradigm for the evaluation of stimulation-evoked somatosensory perception thresholds in rats. 2023 - Journal Article

Awards

Teaching Award - Department of Neuroscience [2023]
APSselect award - American Physiological Society [2019]
Travel Award - International Hearing Loss Conference [2019]
NARSAD Young Investigator Award - Brain & Behavior Research Foundation [2018]
Research Grant for New Investigators - American Speech-Language-Hearing Foundation [2009]

Appointments

Assistant Professor
University of Texas at Dallas [2020–Present]
School of Behavioral and Brain Sciences
Research Assistant Professor
University of Texas at Dallas [2016–2020]
Texas Biomedical Device Center
Research Associate
University of Texas at Dallas [2009–2016]
School of Behavioral and Brain Sciences

News Articles

Vagus Nerve Stimulation Plus Sound May Improve Auditory Processing in Rett, Study Suggests
Nerve Stimulation + Repetitive Sounds Help Improve Hearing
Study Captures Brain’s Activity Processing Speech
Top Journal Publishes Student Brain Researchers

Funding

Enhancing speech processing in a rat model of autism using vagus nerve stimulation
$1,912,500 - NIDCD, NIH [2018/12–2024/11]
The goal of this project is to evaluate whether VNS paired with speech training can reverse the neural and behavioral speech processing deficits observed in a rat model of autism.
Restoring auditory processing in a rat model of Rett syndrome
$400,000 - Eagles Autism Foundation [2022/04–2025/04]
The objective of this proposal is to determine whether auditory training paired with neuromodulator release can reverse the neural and behavioral auditory processing deficits observed in heterozygous Mecp2 rats.
Proteomic analysis of VNS-sound pairing therapy effects on cortical tissue in a rat model of ASD
$49,879 - Autism Research Institute [2024/01–2025/12]
This proposal will provide insight into the proteomic changes associated with novel plasticity-based therapies in treating the severe auditory sensory processing deficits observed in Rett syndrome.
Novel Neuromodulation Therapy to Address Sensory Hypersensitivity in Rett Syndrome
$295,246 - International Rett Syndrome Foundation [2025/02–2027/01]
In this study, we will be using a rat model of Rett syndrome that shows anxiety and heightened responses to sounds and touch. Our first goal is to investigate if we can reduce sensitivity to loud sounds in these rats. Next, we will explore whether we can reduce hypersensitivity to touch. Additionally, we will assess whether VNS therapy can improve anxiety and social interactions.