Hyunjoo Nam

Assistant Professor - Bioengineering

Professional Preparation

Ph. D. - Cellular and Developmental Biology
Harvard University - 1996
M. E. - Biology Education
Seoul National University, Seoul, Korea - 1990
B. S. - Biological Sciences
Seoul National University, Seoul, Korea - 1988

Research Areas

Research Interests
  • Macromolecular X-ray Crystallography
  • Protein Engineering
  • Structural Biology of Virus
  • Protein Biochemistry
  • Protein-DNA Interactions
  • Structural Studies of Molecules Involved Immune Responses


Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.  Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ.   ? - Publication
Mitchell M, Nam HJ, Carter A, McCall A, Rence C, Bennett A, Gurda B, McKenna R, Porter M, Sakai Y, Byrne BJ, Muzyczka N, Aslanidi G, Zolotukhin S, Agbandje-McKenna M. Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9. 2009 Acta Crystallogr. F. 65, 715-718 2009 - Publication
Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A, Johnston J, Debyser Z, Agbandje-McKenna M, Wilson JM. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. 2009. Gene Ther. [Epub ahead of print] 2009 - Publication
Etingov I, Itah R, Mincberg M, Keren-Naus A, Nam HJ, Agbandje-McKenna M, Davis C. An extension of the Minute Virus of Mice tissue tropism. 2008, Virology 379, 245-255. 2008 - Publication
Genis C, Scone P, Kasahara H, Nam HJ. Crystallization and preliminary X-ray analysis of NKX2.5 homeodomain in complex with DNA. 2008, Acta Crystallogr. F. 64, 1079-1082 2008 - Publication
Nam HJ, Genis C, Scone P, Kasahara H. Crystal structure of NKX2.5 homeodomain in complex with ANF-242 motif. 2008, AHA Scientific Scession. 2008 - Publication
Nam HJ, Lane MD, Padron E, Gurda B, McKenna R, Kohlbrenner E, Aslanidi G, Byrne B, Muzyczka N, Zolotukhin S, Agbandje-McKenna M. Structure of Adeno-Associated virus serotype 8, a gene therapy vector. 2007, J. Virol. 81, 12260-12271. (ISI citation: 6) 2007 - Publication
Nam HJ, Gurda-Whitaker B, Gan WY, Ilaria S, McKenna R, Mehta P, Alvarez RA, Agbandje-McKenna M, Identification of the sialic acid structures recognized by minute virus of mice and the role of binding affinity in virulence adaptation, 2006, J. Biol. Chem 281, 25670-25677. (ISI citation: 6) 2006 - Publication
MD, Nam HJ, Padron E, Gurda-Whitaker B, Kohlbrenner E, Aslanidi G, Byrne B, McKenna R, Muzyczka N,  Zolotukhin S,  Agbandje-McKenna M, Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8, 2005, Acta Crystallogr. F 61, 558-561 (ISI citation: 6) 2005 - Publication
Nam HJ, Poy F, Saito, H, and Frederick CA, Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45, 2005, J. Exp. Med  201, 441-452 (ISI citation: 27) 2005 - Publication


Assistant Professor
University of Texas at Dallas, Richardson, TX [2009–Present]
Assistant Scientist
University of Florida, Gainesville, FL [2003–2009]
Research Associate
Harvard University, Boston MA [2001–2002]
Research Associate
Harvard University, Boston MA [1997–1999]
Research Associate
Harvard University, Boston MA [1992–1996]
Research Assitant
Harvard University, Boston MA [1992–1996]
High School Biology Teacher
Sangye High School, Seoul, Korea [1990–1990]
Research Assitant
Biology Education, Seoul National University, Seoul, Korea [1988–1990]

Additional Information

  • American Crystallographic Association
  • American Heart Association
  • 1986 - 1988 - Highest Honor Fellowship
  • 1988 - President's Award. Seoul National University