Gregg Dieckmann

Associate Professor - Chemistry
 
972-883-2903
BE2324
Tags: Inorganic Chemistry

Professional Preparation

Ph.D - Chemistry
University of Michigan - 1995
M.S - Chemistry
University of Michigan - 1995
B.A - Chemistry
DePauw University - 1988
B.A - Computer Science
DePauw University - 1988

Research Areas

Research Description
Using an integrative approach, the Dieckmann Lab utilizes protein design to create simple model systems. These systems provide insights into the functioning of more complex biological systems, or yield new bio/nano hybrid materials. Projects include:

  • Bionanotechnology: designed protein motifs for the noncovalent functionalization of carbon nanotubes
  • Thiolate-rich Zn(II) sites and alkyl transfer: how does protein environment control Zn(II) reactivity
  • DNA-binding domains: probing the molecular basis of gene regulation and DNA repair

Publications

Coutinho, Decio, Alfonso Ortiz-Acevedo, Gregg R. Dieckmann, and Kenneth J. Balkus Jr. 2002. Molecular Imprinting of Mesoporous SBA-15 with Chiral Ruthenium Complexes. Microporous and Mesoporous Materials 54: 249-55. 2002 - Publication
Gandhi, Chris S., Kevin Shuck, James D. Lear, Gregg R. Dieckmann, William F. DeGrado, Robert A. Lamb, and Lawrence H. Pinto. 1999. Cu(II) Inhibition of the Proton Translocation Machinery of the Influenza A Virus M2 Protein. Journal of Biological Chemistry 274: 5474-82. 1999 - Publication
Dieckmann, Gregg R., James D. Lear, Qingfeng Zhong, Michael L. Klein, William F. DeGrado, and Kim A. Sharp. 1999. Exploration of the Structural Features Defining the Conduction Properties of a Synthetic Ion Channel. Biophysical Journal 76: 618-30. 1999 - Publication
Forrest, Lucy R., William F. DeGrado, Gregg R. Dieckmann, and Mark S. P. Sansom. 1998. Influenza A M2 Channel Domain: A Comparison of Two Models. Folding & Design 3: 443- 48. 1998 - Publication
Dieckmann, Gregg R., Donald K. McRorie, James D. Lear, Kim A. Sharp, William F. DeGrado, and Vincent L. Pecoraro. 1998. The Role of Protonation and Metal Chelation Preferences in Defining the Properties of Mercury-Binding Coiled Coils. Journal of Molecular Biology 280: 897-912. 1998 - Publication
Dieckmann, Gregg R., and William F. DeGrado. 1997. Modeling Transmembrane Helical Oligomers. Current Opinion in Structural Biology 7: 486-94. 1997 - Publication
Dieckmann, Gregg R., Donald K. McRorie, David L. Tierney, Lisa M. Utschig, Christopher P. Singer, Thomas V. O'Halloran, James E. Penner-Hahn, William F. DeGrado, and Vincent L. Pecoraro. 1997. De Novo Design of Mercury-Binding Two- and Three-Helical Bundles. Journal of the American Chemical Society 119: 6195-96. 1997 - Publication

Appointments

Associate Head
The University of Texas at Dallas [2009–Present]
Associate Professor,
The University of Texas at Dallas [2005–Present]
Assistant Professor,
The University of Texas at Dallas [1999–2005]
Scientific Consultant
Tetra Tech, Inc., Pasadena, CA [1998–1999]
Postdoctoral Researcher,
University of Pennsylvania [1995–1999]
Graduate Research Assistant,
The University of Michigan [1992–1995]
Educational Software Developer / Administrator,
The University of Michigan [1989–1995]
Graduate Teaching Assistant,
The University of Michigan [1988–1992]

Awards

Faculty Teaching Award - School of Natural Sciences & Mathematics [2016]
Faculty Teaching Award - School of Natural Sciences & Mathematics [2011]

Projects

Modulation of Metal-binding Affinities and Reactivity with Alkylating Agents through Engineered Changes in the Zinc Ribbon Protein L36
2004–2004 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, Harsha S. Kolla, and Matthew Junker. 2004. Modulation of Metal-binding Affinities and Reactivity with Alkylating Agents through Engineered Changes in the Zinc Ribbon Protein L36. Oral presentation at the American Chemical Society, Spring National Meeting: session Bioinorganic Chemistry, March 28-April 1, in Anaheim, CA.
Investigating the Oxidative Stress Response of HeLa Cells Exposed to SWCNTs
2002–2002 Yehia, Hadi, Ray H. Baughman, Gregg R. Dieckmann, Rockford K. Draper, Inga H. Musselman, and Paul Pantano. 2006. Investigating the Oxidative Stress Response of HeLa Cells Exposed to SWCNTs. Presentation at the American Chemical Society, Spring National Meeting, March 26, in Atlanta, GA.
Controlled Assembly of Carbon Nanotubes in Aqueous Solution with Designed Peptides.
2003–2003 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, Alan B. Dalton, Joselito Razal, Jian Chen, Edgar Mu?oz, Inga H. Musselman, Ray H. Baughman, and Rockford K. Draper. 2003. Controlled Assembly of Carbon Nanotubes in Aqueous Solution with Designed Peptides. Oral presentation at the 18th American Peptide Symposium: session Material & Drug Design, July 19-23, in Boston, MA. Biopolymers, 71(3), 300 - 300 O71 (2003).
Computers in Chemical Education
1991–1991 Dieckmann, Gregg R. 1991. Critical Thinking and Achievement in General Chemistry: Reaching and Teaching Large Student Populations. Oral presentation at the National Meeting of the American Chemical Society: session Computers in Chemical Education, August, in New York, NY. Abstracts of Papers of the American Chemical Society, 202, 81- CHED Part 1 (1991).
Effect of Aromatic Content on Peptide/Carbon Nanotube Composite Properties
2002–2002 Ortiz-Acevedo, Alfonso, Vasiliki Zorbas, Alan B. Dalton, Ray H. Baughman, Rockford K. Draper, Inga H. Musselman, and Gregg R. Dieckmann. 2003. Effect of Aromatic Content on Peptide/Carbon Nanotube Composite Properties. Poster presentation at the Strategic Partnership for Research In Nanotechnology (SPRING), 1st Annual Meeting, August 25-27

Additional Information

Chairing Professional Meeting Sessions
1. June 11, 2003, Princeton University; Princeton, NJ, Session "Biophysical Chemistry"
American Chemical Society, Middle Atlantic Regional Meeting

2. April 1, 2004, Anaheim, CA, Session "Environmental Chemistry"
American Chemical Society, Spring National Meeting
Reviewer for Professional Journals
  • Fall 2003 - present Australian Journal of Chemistry
  • Spring 2003 - present Biochemical et Biophysical Acta
  • Spring 2009 - present Biomacromolecules
  • Spring 2005 - present Biopolymers
  • Summer 2007 - present Chemical Communications
  • Spring 2005 - present Chemistry of Materials
  • Fall 2004 - present Current Nanoscience
  • Spring 2005 - present European Biophysical Journal
  • Summer 2004 - present Expert Opinion in Drug Delivery
  • Spring 2000 - present Inorganic Chemistry
  • Summer 2009 - present International Journal of Nanomedicine
  • Fall 2005 - present Journal of Biological Inorganic Chemistry
  • Spring 2007 - present Journal of Materials Chemistry B
  • Spring 2009 - present Journal of Molecular Biology
  • Fall 2004 - present Journal of Nanoscience and Nanotechnology
  • Fall 2003 - present Journal of Peptide Research
  • Summer 2007 - present Journal of Physical Chemistry
  • Spring 2003 - present Journal of the American Chemical Society
  • Spring 2009 - present Journal of Vacuum Science and Technology
  • Summer 2004 - present Langmuir
  • Fall 2005 - present Letters in Organic Chemistry
  • Spring 2004 - present Nano Letters
  • Spring 2006 - present Organic Letters
  • Summer 2009 - present Proceedings of the National Academy of Science
  • Spring 2004 - present Protein Science
  • Spring 2009 - present Science
  • Spring 2005 - present Tetrahedron
  • Summer 2004 - present Tetrahedron Letters
Doctoral advisement/direction

1. Kristine Danowski, left group Summer 2006
Project: Reversible Cyclic Peptides, Carbon Nanotubes, and Their Interactions with Living Cells
2. Kevin T. Greene, left program Fall 2003
Project: Use of Domain Fragmentation and Protein Design to Study Protein-Protein Interactions
3. Jane H. Nguyen, May 2007 - present
Project: (1) TEM/cryo-TEM of peptide/SWNT dispersions
(2) new amphiphilic periodicities for SWNT interactions
4. Alfonso Ortiz-Acevedo, awarded April 2008
Thesis: Understanding Peptide Interactions with Carbon Nanotubes
5. Hui Xie, awarded August 2005
Thesis: Understanding and Improving Peptide Non-covalent Solubilization of Single-Walled Carbon Nanotubes

News Articles

Chemistry, Literature Instructors Recognized for Classroom Excellence

Two University of Texas at Dallas faculty members have earned The University of Texas System Board of Regents’ highest honor.
Dr. Gregg Dieckmann, associate professor of chemistry in the School of Natural Sciences and Mathematics, and Dr. Peter Ingrao, clinical assistant professor of literature in the School of Arts and Humanities, are recipients of the 2018 Regents’ Outstanding Teaching Award (ROTA). They are among 27 ROTA winners from the UT System’s 14 academic and health institutions who will be recognized at a dinner Thursday, Aug. 9, in Austin. Each honoree receives $25,000.

Chemistry Prof Is Honored for Stirring Young Minds
The School of Natural Sciences and Mathematics has honored Dr. Gregg Dieckmann with the 2010-2011 Outstanding Teaching Award for his efforts in encouraging students and creating a successful learning environment.

Dieckmann, associate professor of chemistry, said he appreciated the recognition from students and colleagues for something he loves doing. He has taught at UT Dallas for more than a decade.

Funding

Predicting, Testing, and Neutralizing Nanoparticle Toxicity
$120,000 - Semiconductor Research Corporation [2009–2010]
Nanotechnology in Cancer
$1,000,000 - Department of Defense, Telemedicine & Advanced Technology Research Center [2008–2009]
Carbon Nanotubes in Cancer [one project of a program project entitled "Interdisciplinary Studies on the Combat Readiness and Health Issues Faced by Military Personnel", S. R. Goodman, PI]
$210,000 - Department of Defense, U.S. Army Medical Research Acquisition Activity [2007–2008]
Peptide-coated Nanotubes: Toxicity and Targeted Cell Ablation
$1,050,000 - Human Frontier Science Program: Young investigators Grant [2005–2008]
Investigation of the Factors Affecting Reactivity of Thiolate-rich Zn(II) Sites in Proteins Gregg R. Dieckmann (PI)
$80,000 - The American Chemical Society: The Petroleum Research Fund (type AC) [2004–2006]