Gregg Dieckmann

Associate Professor - Chemistry
 
972-883-2903
BE2324
Tags: Inorganic Chemistry

Professional Preparation

Ph.D - Chemistry
University of Michigan - 1995
M.S - Chemistry
University of Michigan - 1995
B.A - Chemistry
DePauw University - 1988
B.A - Computer Science
DePauw University - 1988

Research Areas

Research Description
Using an integrative approach, the Dieckmann Lab utilizes protein design to create simple model systems. These systems provide insights into the functioning of more complex biological systems, or yield new bio/nano hybrid materials. Projects include:

  • Bionanotechnology: designed protein motifs for the noncovalent functionalization of carbon nanotubes
  • Thiolate-rich Zn(II) sites and alkyl transfer: how does protein environment control Zn(II) reactivity
  • DNA-binding domains: probing the molecular basis of gene regulation and DNA repair

Publications

Samarajeewa, D.R.; Dieckmann, G.R.; Nielsen, S.O.; Musselman, I.H. “Modifying the Electronic Properties of Single-Walled Carbon Nanotubes Using Designed Surfactant Peptides”, Nanoscale (2012) 4: 4544-4554. 2012 - Publication
Chiu, C.-C.; Maher, M.C.; Dieckmann, G.R.; Nielsen, S.O. “Molecular Dynamics Study of a Carbon Nanotube-Binding Reversible Cyclic Peptide”, ACSNano (2010) 4: 2539 - 2546. 2010 - Publication
Chiu, Chi-Cheng, Gregg R. Dieckmann, and Steven O. Nielsen. 2009. Role of Peptide-Peptide Interactions in Stabilizing Peptide-Wrapped Single-Walled Carbon Nanotubes: A Molecular Dynamics Study. Biopolymers: Peptide Science 92(3): 156-63. 2009 - Publication
Becraft, Eric J., Anton S. Klimenko, and Gregg R. Dieckmann. 2009. Influence of Alternating L-/D-Amino Acid Chiralities and Disulfide Bond Geometry on the Capacity of Cysteine-Containing Reversible Cyclic Peptides to Disperse Carbon Nanotubes. Biopolymers: Peptide Science 92(3): 212-21. 2009 - Publication
Nicolosi, Valeria, Helen Cathcart, Alan B. Dalton, Damian Aherne, Gregg R. Dieckmann, and Jonathan N. Coleman. 2008. Spontaneous Exfoliation of Single Walled Carbon Nanotubes Dispersed Using a Designed Amphiphilic Peptide. Biomacromolecules 9(2): 598-602. 2008 - Publication
Chiu, Chi-Cheng, Gregg R. Dieckmann, and Steven O. Nielsen. 2008. Molecular Dynamics Study of a Nanotube-Binding Amphiphilic Helical Peptide at Different Hydrophilic/Hydrophobic Interfaces. Journal of Physical Chemistry B 112(51): 16326-33. 2008 - Publication
Xie, Hui, Eric J. Becraft, Ray H. Baughman, Alan B. Dalton, and Gregg R. Dieckmann. 2008. Ranking the Affinity of Aromatic Residues for Carbon Nanotubes by Using Designed Surfactant Peptides. Journal of Peptide Science, special issue Peptides in Nanotechnology 14(2): 139-51. 2008 - Publication
Chin Shook-Fong, Ray H. Baughman, Alan B. Dalton, Gregg R. Dieckmann, Rockford K. Draper, Carole Mikoryak, Inga H. Musselman, Vasiliki Z. Poenitzsch, Hui Xie, and Paul Pantano. 2007. Amphiphilic Helical Peptide Enhances the Uptake of Single-Walled Carbon Nanotubes by Living Cells. Experimental Biology and Medicine 232: 1236-44. 2007 - Publication
Poenitzsch, Vasiliki Z., David C. Winters, Hui Xie, Gregg R. Dieckmann, Alan B. Dalton, and Inga H. Musselman. 2007. Effect of Electron-Donating and Electron-Withdrawing Groups on Peptide/Single-Walled Carbon Nanotube Interactions. Journal of the American Chemical Society 129: 14724-32. 2007 - Publication
Yehia, Hadi N., Rockford K. Draper, Carole A. Mikoryak, Erin K. Walker, Pooja Bajaj, Inga H. Musselman, Meredith C. Daigrepont, Gregg R. Dieckmann, and Paul Pantano. 2007. Single- Walled Carbon Nanotube Interactions with HeLa Cells. Journal of Nanobiotechnology 5, 8 DOI: 10.1186/1477-3155-5-8. 2007 - Publication

Appointments

Associate Head
The University of Texas at Dallas [2009–Present]
Associate Professor,
The University of Texas at Dallas [2005–Present]
Assistant Professor,
The University of Texas at Dallas [1999–2005]
Scientific Consultant
Tetra Tech, Inc., Pasadena, CA [1998–1999]
Postdoctoral Researcher,
University of Pennsylvania [1995–1999]
Graduate Research Assistant,
The University of Michigan [1992–1995]
Educational Software Developer / Administrator,
The University of Michigan [1989–1995]
Graduate Teaching Assistant,
The University of Michigan [1988–1992]

Awards

Faculty Teaching Award - School of Natural Sciences & Mathematics [2016]
Faculty Teaching Award - School of Natural Sciences & Mathematics [2011]

Projects

An Approach Towards Membrane Fusion Inhibition
2001–2001 Ortiz-Acevedo, Alfonso, and Gregg R. Dieckmann. 2001. An Approach Towards Membrane Fusion Inhibition. Poster presentation at the Ninth Annual Texas Protein Folders Meeting, April 6-8, in Navasota, TX.
Noncovalent Functionalization of Carbon Nanotubes Using Designed Amphiphilic Peptides
2004–2004 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, Hui Xie, Alan B. Dalton, Vasiliki Zorbas, Ray H. Baughman, Rockford K. Draper, and Inga H. Musselman. 2004. Noncovalent Functionalization of Carbon Nanotubes Using Designed Amphiphilic Peptides. Poster presentation at the Gordon Research Conference: Nanostructure Fabrication, July 18-22, in Tilton, NH.
Metals in Biology
2001–2001 Dieckmann, Gregg R., Regan L. Reece, and Alfonso Ortiz. 2001. Modeling the Hg(II)-binding Site of the Metalloregulatory Protein MerR. Poster presentation at the Gordon esearch Conference: Metals in Biology, January 21-26, in Ventura, CA.
Designing Helixbinding Receptors Through Domain Fragmentation
2001–2001 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, and David A. Stidd. 2001. Designing Helixbinding Receptors Through Domain Fragmentation. Poster presentation at the Fifteenth Symposium of The Protein Society: session Protein Design, Mutagenesis and Evolution, July 28-August 1, in Philadelphia, PA. Protein Science, 10(Suppl. 2), 122 (2001).
Designing Helix-binding Receptors through Domain Fragmentation
2002–2002 Greene, Kevin T., and Gregg R. Dieckmann. 2002. Designing Helix-binding Receptors through Domain Fragmentation. Poster presentation at the Tenth Annual Texas Protein Folders Meeting, April 19-21, in Navasota, TX.

Additional Information

Chairing Professional Meeting Sessions
1. June 11, 2003, Princeton University; Princeton, NJ, Session "Biophysical Chemistry"
American Chemical Society, Middle Atlantic Regional Meeting

2. April 1, 2004, Anaheim, CA, Session "Environmental Chemistry"
American Chemical Society, Spring National Meeting
Reviewer for Professional Journals
  • Fall 2003 - present Australian Journal of Chemistry
  • Spring 2003 - present Biochemical et Biophysical Acta
  • Spring 2009 - present Biomacromolecules
  • Spring 2005 - present Biopolymers
  • Summer 2007 - present Chemical Communications
  • Spring 2005 - present Chemistry of Materials
  • Fall 2004 - present Current Nanoscience
  • Spring 2005 - present European Biophysical Journal
  • Summer 2004 - present Expert Opinion in Drug Delivery
  • Spring 2000 - present Inorganic Chemistry
  • Summer 2009 - present International Journal of Nanomedicine
  • Fall 2005 - present Journal of Biological Inorganic Chemistry
  • Spring 2007 - present Journal of Materials Chemistry B
  • Spring 2009 - present Journal of Molecular Biology
  • Fall 2004 - present Journal of Nanoscience and Nanotechnology
  • Fall 2003 - present Journal of Peptide Research
  • Summer 2007 - present Journal of Physical Chemistry
  • Spring 2003 - present Journal of the American Chemical Society
  • Spring 2009 - present Journal of Vacuum Science and Technology
  • Summer 2004 - present Langmuir
  • Fall 2005 - present Letters in Organic Chemistry
  • Spring 2004 - present Nano Letters
  • Spring 2006 - present Organic Letters
  • Summer 2009 - present Proceedings of the National Academy of Science
  • Spring 2004 - present Protein Science
  • Spring 2009 - present Science
  • Spring 2005 - present Tetrahedron
  • Summer 2004 - present Tetrahedron Letters
Doctoral advisement/direction

1. Kristine Danowski, left group Summer 2006
Project: Reversible Cyclic Peptides, Carbon Nanotubes, and Their Interactions with Living Cells
2. Kevin T. Greene, left program Fall 2003
Project: Use of Domain Fragmentation and Protein Design to Study Protein-Protein Interactions
3. Jane H. Nguyen, May 2007 - present
Project: (1) TEM/cryo-TEM of peptide/SWNT dispersions
(2) new amphiphilic periodicities for SWNT interactions
4. Alfonso Ortiz-Acevedo, awarded April 2008
Thesis: Understanding Peptide Interactions with Carbon Nanotubes
5. Hui Xie, awarded August 2005
Thesis: Understanding and Improving Peptide Non-covalent Solubilization of Single-Walled Carbon Nanotubes

News Articles

Chemistry, Literature Instructors Recognized for Classroom Excellence

Two University of Texas at Dallas faculty members have earned The University of Texas System Board of Regents’ highest honor.
Dr. Gregg Dieckmann, associate professor of chemistry in the School of Natural Sciences and Mathematics, and Dr. Peter Ingrao, clinical assistant professor of literature in the School of Arts and Humanities, are recipients of the 2018 Regents’ Outstanding Teaching Award (ROTA). They are among 27 ROTA winners from the UT System’s 14 academic and health institutions who will be recognized at a dinner Thursday, Aug. 9, in Austin. Each honoree receives $25,000.

Chemistry Prof Is Honored for Stirring Young Minds
The School of Natural Sciences and Mathematics has honored Dr. Gregg Dieckmann with the 2010-2011 Outstanding Teaching Award for his efforts in encouraging students and creating a successful learning environment.

Dieckmann, associate professor of chemistry, said he appreciated the recognition from students and colleagues for something he loves doing. He has taught at UT Dallas for more than a decade.

Funding

Predicting, Testing, and Neutralizing Nanoparticle Toxicity
$120,000 - Semiconductor Research Corporation [2009–2010]
Nanotechnology in Cancer
$1,000,000 - Department of Defense, Telemedicine & Advanced Technology Research Center [2008–2009]
Carbon Nanotubes in Cancer [one project of a program project entitled "Interdisciplinary Studies on the Combat Readiness and Health Issues Faced by Military Personnel", S. R. Goodman, PI]
$210,000 - Department of Defense, U.S. Army Medical Research Acquisition Activity [2007–2008]
Peptide-coated Nanotubes: Toxicity and Targeted Cell Ablation
$1,050,000 - Human Frontier Science Program: Young investigators Grant [2005–2008]
Investigation of the Factors Affecting Reactivity of Thiolate-rich Zn(II) Sites in Proteins Gregg R. Dieckmann (PI)
$80,000 - The American Chemical Society: The Petroleum Research Fund (type AC) [2004–2006]