Gregg Dieckmann

Associate Professor - Chemistry
 
972-883-2903
BE2324
Tags: Inorganic Chemistry

Professional Preparation

Ph.D - Chemistry
University of Michigan - 1995
M.S - Chemistry
University of Michigan - 1995
B.A - Chemistry
DePauw University - 1988
B.A - Computer Science
DePauw University - 1988

Research Areas

Research Description
Using an integrative approach, the Dieckmann Lab utilizes protein design to create simple model systems. These systems provide insights into the functioning of more complex biological systems, or yield new bio/nano hybrid materials. Projects include:

  • Bionanotechnology: designed protein motifs for the noncovalent functionalization of carbon nanotubes
  • Thiolate-rich Zn(II) sites and alkyl transfer: how does protein environment control Zn(II) reactivity
  • DNA-binding domains: probing the molecular basis of gene regulation and DNA repair

Publications

Samarajeewa, D.R.; Dieckmann, G.R.; Nielsen, S.O.; Musselman, I.H. “Modifying the Electronic Properties of Single-Walled Carbon Nanotubes Using Designed Surfactant Peptides”, Nanoscale (2012) 4: 4544-4554. 2012 - Publication
Chiu, C.-C.; Maher, M.C.; Dieckmann, G.R.; Nielsen, S.O. “Molecular Dynamics Study of a Carbon Nanotube-Binding Reversible Cyclic Peptide”, ACSNano (2010) 4: 2539 - 2546. 2010 - Publication
Chiu, Chi-Cheng, Gregg R. Dieckmann, and Steven O. Nielsen. 2009. Role of Peptide-Peptide Interactions in Stabilizing Peptide-Wrapped Single-Walled Carbon Nanotubes: A Molecular Dynamics Study. Biopolymers: Peptide Science 92(3): 156-63. 2009 - Publication
Becraft, Eric J., Anton S. Klimenko, and Gregg R. Dieckmann. 2009. Influence of Alternating L-/D-Amino Acid Chiralities and Disulfide Bond Geometry on the Capacity of Cysteine-Containing Reversible Cyclic Peptides to Disperse Carbon Nanotubes. Biopolymers: Peptide Science 92(3): 212-21. 2009 - Publication
Nicolosi, Valeria, Helen Cathcart, Alan B. Dalton, Damian Aherne, Gregg R. Dieckmann, and Jonathan N. Coleman. 2008. Spontaneous Exfoliation of Single Walled Carbon Nanotubes Dispersed Using a Designed Amphiphilic Peptide. Biomacromolecules 9(2): 598-602. 2008 - Publication
Chiu, Chi-Cheng, Gregg R. Dieckmann, and Steven O. Nielsen. 2008. Molecular Dynamics Study of a Nanotube-Binding Amphiphilic Helical Peptide at Different Hydrophilic/Hydrophobic Interfaces. Journal of Physical Chemistry B 112(51): 16326-33. 2008 - Publication
Xie, Hui, Eric J. Becraft, Ray H. Baughman, Alan B. Dalton, and Gregg R. Dieckmann. 2008. Ranking the Affinity of Aromatic Residues for Carbon Nanotubes by Using Designed Surfactant Peptides. Journal of Peptide Science, special issue Peptides in Nanotechnology 14(2): 139-51. 2008 - Publication
Chin Shook-Fong, Ray H. Baughman, Alan B. Dalton, Gregg R. Dieckmann, Rockford K. Draper, Carole Mikoryak, Inga H. Musselman, Vasiliki Z. Poenitzsch, Hui Xie, and Paul Pantano. 2007. Amphiphilic Helical Peptide Enhances the Uptake of Single-Walled Carbon Nanotubes by Living Cells. Experimental Biology and Medicine 232: 1236-44. 2007 - Publication
Poenitzsch, Vasiliki Z., David C. Winters, Hui Xie, Gregg R. Dieckmann, Alan B. Dalton, and Inga H. Musselman. 2007. Effect of Electron-Donating and Electron-Withdrawing Groups on Peptide/Single-Walled Carbon Nanotube Interactions. Journal of the American Chemical Society 129: 14724-32. 2007 - Publication
Yehia, Hadi N., Rockford K. Draper, Carole A. Mikoryak, Erin K. Walker, Pooja Bajaj, Inga H. Musselman, Meredith C. Daigrepont, Gregg R. Dieckmann, and Paul Pantano. 2007. Single- Walled Carbon Nanotube Interactions with HeLa Cells. Journal of Nanobiotechnology 5, 8 DOI: 10.1186/1477-3155-5-8. 2007 - Publication

Appointments

Associate Head
The University of Texas at Dallas [2009–Present]
Associate Professor,
The University of Texas at Dallas [2005–Present]
Assistant Professor,
The University of Texas at Dallas [1999–2005]
Scientific Consultant
Tetra Tech, Inc., Pasadena, CA [1998–1999]
Postdoctoral Researcher,
University of Pennsylvania [1995–1999]
Graduate Research Assistant,
The University of Michigan [1992–1995]
Educational Software Developer / Administrator,
The University of Michigan [1989–1995]
Graduate Teaching Assistant,
The University of Michigan [1988–1992]

Awards

Faculty Teaching Award - School of Natural Sciences & Mathematics [2016]
Faculty Teaching Award - School of Natural Sciences & Mathematics [2011]

Projects

Modulation of Metal-binding Affinities and Reactivity with Alkylating Agents through Engineered Changes in the Zinc Ribbon Protein L36
2004–2004 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, Harsha S. Kolla, and Matthew Junker. 2004. Modulation of Metal-binding Affinities and Reactivity with Alkylating Agents through Engineered Changes in the Zinc Ribbon Protein L36. Oral presentation at the American Chemical Society, Spring National Meeting: session Bioinorganic Chemistry, March 28-April 1, in Anaheim, CA.
Investigating the Oxidative Stress Response of HeLa Cells Exposed to SWCNTs
2002–2002 Yehia, Hadi, Ray H. Baughman, Gregg R. Dieckmann, Rockford K. Draper, Inga H. Musselman, and Paul Pantano. 2006. Investigating the Oxidative Stress Response of HeLa Cells Exposed to SWCNTs. Presentation at the American Chemical Society, Spring National Meeting, March 26, in Atlanta, GA.
Controlled Assembly of Carbon Nanotubes in Aqueous Solution with Designed Peptides.
2003–2003 Dieckmann, Gregg R., Alfonso Ortiz-Acevedo, Alan B. Dalton, Joselito Razal, Jian Chen, Edgar Mu?oz, Inga H. Musselman, Ray H. Baughman, and Rockford K. Draper. 2003. Controlled Assembly of Carbon Nanotubes in Aqueous Solution with Designed Peptides. Oral presentation at the 18th American Peptide Symposium: session Material & Drug Design, July 19-23, in Boston, MA. Biopolymers, 71(3), 300 - 300 O71 (2003).
Computers in Chemical Education
1991–1991 Dieckmann, Gregg R. 1991. Critical Thinking and Achievement in General Chemistry: Reaching and Teaching Large Student Populations. Oral presentation at the National Meeting of the American Chemical Society: session Computers in Chemical Education, August, in New York, NY. Abstracts of Papers of the American Chemical Society, 202, 81- CHED Part 1 (1991).
Effect of Aromatic Content on Peptide/Carbon Nanotube Composite Properties
2002–2002 Ortiz-Acevedo, Alfonso, Vasiliki Zorbas, Alan B. Dalton, Ray H. Baughman, Rockford K. Draper, Inga H. Musselman, and Gregg R. Dieckmann. 2003. Effect of Aromatic Content on Peptide/Carbon Nanotube Composite Properties. Poster presentation at the Strategic Partnership for Research In Nanotechnology (SPRING), 1st Annual Meeting, August 25-27

Additional Information

Bachelors Advisement/Direction

1. Aasim Afzal, Fall 2006 - Spring 2008
Project: Synthesis and characterization of permanently cyclic peptide models for RC7
2. Fesshatison Argow, Fall 2007 - Spring 2009
Project: Effect of solvent conditions (alcohol/water mixtures) on dispersion of carbon nanotubes by reversible cyclic peptides (RC3-Cys)
3. Laura Bartran, awarded December 2006
Project: Effect of changing location of His in coordination site of L3
4. Volney Brand, Fall 2000 - Spring 2001
Project: Studying the role of the Zn site in RPB10
5. Kyle Bruner, June 2009 - Current
Project: Separation of RCP/SWNT dispersions using magnetic particle (or gold particle) labeling of biotin-functionalized RCPs
6. Virginia Buhl, Summer 2006 - Sept. 2007
Project: His derivatives of nano-1 and their interactions with carbon nanotubes
7. Qishen Chang, Fall 2009 - present
Project: to be determined
8. Brendon Eaton, Spring 2008 - Spring 2009
Project: Incorporation of N-glycine derivatives into RCP-Cys peptides [N-norleucine-Gly derivatives]
9. Geoff Giordano, Fall 2001 - Fall 2002
Project: Interaction of designed peptides with carbon nanotubes
10. Jeff Jones, Summer 2000 - Spring 2002
Project: Study of a 3-Helix bundle containing a thiolate-rich metal-binding site
11. Anton Klimenko, awarded May 2008
Project: Use of alternate alcohols for the modulation of nano-1 helicity, self association and interactions with SWNTs
12. Parimala Marpaka, Fall 2004
Project: Studying Zn(II) binding in a novel Zn(II)-binding domain
13. Tobin Medrano, Spring 2000 - Spring 2001
Project: Design of novel 3-helix bundles that bind DNA
14. Michael E. Meerbrey, Fall 2009 - present
Project: Stabilization of RCP/SWNT dispersions in PBS conditions
15. Jane H. Nguyen, awarded May 2004
Thesis: Effect of Methylation on the Metal-binding Properties of Derivatives of the Protein L36
16. Anthony Pham, Spring 2002 - Fall 2003
Project: Design of models for the mercury-binding site in the protein MerR
17. Jesse C. Qiao, August 2003 - Summer 2004
Project: Synthesis and characterization of cyclic peptides
18. Regan L. Reece, Spring 2000 - Spring 2001
Project: Investigation of mercury binding in MerR monomer
19. Mona Sadeghpour, Spring 2005 - Summer 2006
Project: mRNA display of peptides for carbon nanotube functionalization
20. Suhail H. Sheikha, awarded May 2001
Thesis: Design of helical targets for membrane fusion inhibitors
21. Areeg Siddig, Spring 2008 - Spring 2009
Project: Cross-linking of nano-1 using oximes
22. Ji Song, Fall 2004 - Spring 2005
Project: Synthesis and characterization of cyclic β-hairpin peptides
23. David A. Stidd, awarded May 2002
Thesis: Use of Protein Design in the Engineering of Novel Protein/Protein and Protein/DNA Complexes
24. Shane Stone, Spring 2008 - Summer 2008
Project: Synthesis of side chain-modified (branched) reversible cyclic peptides
25. Jessica Tolbert, Spring 2002 - Fall 2003
Project: Do 3-coordinate "Zn(II)-binding sites" in L36 derivatives actually bind zinc?
26. Lynn Trinh, Spring 2008
Project: Incorporation of short Lys-derivatives into RC7-Cys

Editorial Boards
  • 1. July 2004 - present Member of Editorial Board: Current Nanoscience
  • 2. Summer 2005 - present Member of Editorial Board: Experimental Biology and
Professional recognitions and honors (study, teaching, research, service):
  • Outstanding Instructor Recognition, 2006, College Board Advanced Placement- Best Practices Course Study
  • Editorial Board, Experimental Biology and Medicine, 2006-present
  • Editorial Board, Current Nanoscience, 2004-present
  • Milton Tamres Outstanding Teaching Award, 1992, The University of Michigan, Department of Chemistry, Ann Arbor, MI
  • Baer Teaching Fellowship, 1988-1989, The University of Michigan, Department of Chemistry, Ann Arbor, MI

News Articles

Chemistry, Literature Instructors Recognized for Classroom Excellence

Two University of Texas at Dallas faculty members have earned The University of Texas System Board of Regents’ highest honor.
Dr. Gregg Dieckmann, associate professor of chemistry in the School of Natural Sciences and Mathematics, and Dr. Peter Ingrao, clinical assistant professor of literature in the School of Arts and Humanities, are recipients of the 2018 Regents’ Outstanding Teaching Award (ROTA). They are among 27 ROTA winners from the UT System’s 14 academic and health institutions who will be recognized at a dinner Thursday, Aug. 9, in Austin. Each honoree receives $25,000.

Chemistry Prof Is Honored for Stirring Young Minds
The School of Natural Sciences and Mathematics has honored Dr. Gregg Dieckmann with the 2010-2011 Outstanding Teaching Award for his efforts in encouraging students and creating a successful learning environment.

Dieckmann, associate professor of chemistry, said he appreciated the recognition from students and colleagues for something he loves doing. He has taught at UT Dallas for more than a decade.

Funding

Predicting, Testing, and Neutralizing Nanoparticle Toxicity
$120,000 - Semiconductor Research Corporation [2009–2010]
Nanotechnology in Cancer
$1,000,000 - Department of Defense, Telemedicine & Advanced Technology Research Center [2008–2009]
Carbon Nanotubes in Cancer [one project of a program project entitled "Interdisciplinary Studies on the Combat Readiness and Health Issues Faced by Military Personnel", S. R. Goodman, PI]
$210,000 - Department of Defense, U.S. Army Medical Research Acquisition Activity [2007–2008]
Peptide-coated Nanotubes: Toxicity and Targeted Cell Ablation
$1,050,000 - Human Frontier Science Program: Young investigators Grant [2005–2008]
Investigation of the Factors Affecting Reactivity of Thiolate-rich Zn(II) Sites in Proteins Gregg R. Dieckmann (PI)
$80,000 - The American Chemical Society: The Petroleum Research Fund (type AC) [2004–2006]