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Duane D. Winkler

Duane D. Winkler

Associate Professor - Biological Sciences

Professional Preparation

PhD - Biochemistry
University of Texas - Health - 2009
BS - Biochemistry & Genetics
Texas A&M University - 2003

Research Areas

Structural Biology
Biochemistry and Biophysics
X-ray Crystallography


Mutations in Superoxide Dismutase 1 (Sod1) Linked to Familial Amyotrophic Lateral Sclerosis Can
Disrupt High-Affinity Zinc-Binding Promoted by the Copper Chaperone for Sod1 (Ccs) 2020 - Molecules
"Copper Sources for Sod1 Activation" 2020 - Antioxidants
“The yeast copper chaperone for copper-zinc superoxide dismutase (CCS1) is a multifunctional chaperone promoting all levels of SOD1 maturation.” 2019 - JBC
“The defined toxin-binding region of the cadherin G-protein coupled receptor BT-R1, for the active Cry1Ab toxin from Bacillus thuringiensis.” 2019 - JPB
“Quantifying the Interaction between Copper-Zinc Superoxide Dismutase (Sod1) and its Copper Chaperone (Ccs1).” 2018 - JPB
“Interaction of Fluorescently Labeled Cadherin G-Protein-coupled Receptor with the Cry1Ab Toxin of Bacillus thuringiensis.” 2018 - JPB
“Copper-zinc Superoxide Dismutase is Activated Through a Sulfenic Acid Intermediate at a Copper-ion Entry Site.” 2017 - JBC


Associate Head
Biological Sciences [–Present]


Molecular Mechanisms of Sod1 Maturation Processes
Structure-function Based Rational Design of Insecticide(s)