Ruth L. Kirschstein NRSA Postdoctoral Fellow
University of California, Berkeley - 2023
Professional Preparation
PhD - Chemistry
University of Illinois at Urbana-Champaign - 2020
University of Illinois at Urbana-Champaign - 2020
BS - Chemistry
Northeastern University - 2014
Northeastern University - 2014
Research Areas
The mission of the Delaney Lab is to understand the fundamental patterns of reactivity that underlie organometallic chemistry and use that insight to develop new methods for chemical synthesis. We are particularly interested in new methods to produce saturated heterocycles, given the prevalence of that motif in pharmaceutical and agrochemical products. Members of the group will learn the techniques required for the synthesis of sensitive organometallic compounds, skills associated with the development of new synthetic methods, strategies for the elucidation of reaction mechanisms, and more. The experience gained will prepare students for industry careers in medicinal, process, industrial, or agrochemical chemistry, or to run independent research laboratories in academia.Publications
Potassium Trimethylsilanolate-Promoted, Anhydrous Suzuki–Miyaura Cross-Coupling Reaction Proceeds via the “Boronate Mechanism”: Evidence for the Alternative Fork in the Trail. J. Am. Chem. Soc. 2022 - Journal Article
Heteroaryl-Heteroaryl, Suzuki-Miyaura, Anhydrous Cross-Coupling Reactions Enabled by Trimethyl Borate. J. Am. Chem. Soc. 2021 - Journal Article
Anhydrous, Homogeneous, Suzuki-Miyaura Cross-Coupling of Boronic Esters using Potassium Trimethylsilanolate. Org. Synth. 2020 - Journal Article
Chemoselective Tertiary C–H Hydroxylation for Late-Stage Functionalization with Mn(PDP)/Chloroacetic Acid Catalysis. Adv. Synth. Catal. 2020 - Journal Article
Potassium Trimethylsilanolate Enables Rapid, Homogeneous, Suzuki-Miyaura Cross-Coupling of Boronic Esters. ACS Catal. 2020 - Journal Article
A Dinuclear Mechanism Implicated in Controlled Carbene Polymerization. J. Am. Chem. Soc. 2019 - Journal Article
Elucidating the Role of the Boronic Esters in the Suzuki-Miyaura Reaction: Structural, Kinetic, and Computational Investigations. J. Am. Chem. Soc. 2018 - Journal Article
Kinetics of Phosphine Substitution in CpRu(PPh3)2X (X = Cl, Br, I, N3 and NCO). RSC Adv. 2017 - Journal Article
Awards
Ruth L. Kirschstein NRSA Postdoctoral Fellowship. (NIH F32) - National Institutes of Health [2021]
Denmark Group Kobayashi Student Mentorship Award - Denmark Group [2019]
J. C. Martin Memorial Student Travel Award - University of Illinois at Urbana-Champaign [2019]
Affiliations
Assistant Professor of Chemistry
2023/08University of Texas at Dallas