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Professional Preparation
Ph.D. - Psychology Georgia Institute of Technology - 1994
M.A. - Psychology Duke University - 1989
B.A. - Psychology New York University - 1983
Publications
Shokri-Kojori, E., Motes, M., Rypma, B. and Krawczyk, D. (2012). The network architecture of cortical processing in visuo-spatial reasoning. Nature Scientific Reports, 2, 411. 2012 - Publication
Bennett, I.J., Motes, M.A., Rao, N.K. and Rypma, B. (2012). Relationships between white matter integrity and visual search in healthy aging. Neurobiology of Aging, 33, 433.e21-e31. 2012 - Publication
Hutchison, J.L., Hubbard, T.L., Ferrandino, B., Brigante, R., Wright, J.M. and Rypma, B. (2012). Auditory memory distortion for spoken prose. Journal of Experimental Psychology: Learning, Memory and Cognition, in press. 2012 - Publication
Kannurpatti, S.S., Rypma, B. and Biswal, B.B. (2012). Prediction of task-related BOLD fMRI with amplitude signatures of resting-state fMRI. Frontiers in Systems Neuroscience, 6:7. 2012 - Publication
Hutchison, J.L., Lu, H. and Rypma, B. (2012). Neural mechanisms of age-related slowing: The CBF/CMRO2 ratio mediates age-differences in BOLD signal and human performance. Cerebral Cortex, in press. 2012 - Publication
Di, X., Kannurpatti, S.S., Rypma, B. and Biswal, B.B. (2012). Calibrating BOLD fMRI activation with neurovascular and anatomical constraints. Cerebral Cortex, in press. 2012 - Publication
Kannurpatti, S.S., Motes, M.A., Rypma, B. and Biswal, B.B. (2011). Non-neural BOLD variability in block and event-related paradigms. Magnetic Resonance Imaging, 29, 140-146. 2011 - Publication
Motes, M.A., Biswal, B.B. and Rypma, B. (2011). Age-dependent relationships between prefrontal cortex activation and processing speed. Cognitive Neuroscience, 2, 1-10. 2011 - Publication
Appointments
Associate Professor The University of Texas at Dallas [2006–Present]
Associate Professor University of Texas-Southwestern Medical Center [2006–Present]
Assistant Professor Rutgers University [2001–2006]
Clinical Assistant Professor University of Medicine and Dentistry of New Jersey [2001–2006]
Associate Research Scientist University of California-Berkeley [2000–2001]
Postdoctoral Research Fellow University of Pennsylvania [1997–2000]
NRSA Postdoctoral Research Fellow Stanford University [1994–1997]
Research Assistant Georgia Institute of Technology [1989–1994]
Research Assistant Duke University [1989–1989]
Research Associate New York University Medical Center [1987–1987]
Projects
Isolating neural mechanisms of age-related cognitive change using fMRI.
1999–1999Rypma, B. (1999). Psychology Dept. Colloquium, University of Delaware, Newark, DE.
Studies of working memory processes using fMRI.
1999–1999Rypma, B. (1999). Psychology Department Colloquium, University of Aberdeen, Aberdeen, Scotland.
FMRI studies of human working memory.
1999–1999Rypma, B. (1999). Universitatsklinikum Ulm, University of Ulm, Ulm, Germany.
Neural correlates of human working memory: FMRI studies.
1999–1999Rypma, B. (1999). Psychology Department Colloquium, Brooklyn College, Brooklyn, NY.
Isolating the neural mechanisms of age-related changes in human working memory.
2000–2000Rypma, B. (2000). Psychology Dept. Colloquium, University of Illinois, Urbana-Champai gn, IL.
Additional Information
Professional recognitions, honors, memberships
Busch Biomedical Sciences Research Award, 2005, Rutgers University
Johnson & Johnson Pioneers in Science Award, 2005, Johnson & Johnson
Siemens Award for Innovative Techr1ology Research, 2003, Siemens
American Federation of Aging Research Award, 1999, American Federation of Aging Research
National Research Service Award, 1994, National lnstitute on Aging
Georgia Tech Student Foundation Award, 1991, Georgia Tech Student Foundation
Psychology Dept. Award for Distinguished Research, 1984, New York University Psychology Dept. .
University Honors Scholar, 1983, New York University
Citrin Award for Outstanding Honors Thesis, 1983, New York University Psychology Dept.
Dean's Outstanding Service Award, 1983, New York University
Honors in Psychology, 1983, New York University
Deans List, 1982-83, New York University
Psychology Dept. Award for Distinguished Research, 1982, New York University Psychology Dept.
Society for Neuroscience, 1995
Cognitive Neuroscience Society, 1995
American Psychological Association, 1994
Sigma Xi (Associate), 1994
Psi Chi, 1982
Administration and Curricular Development
UTD/UTSW Faculty Liaison 9/06-present
UTD Human Neuroscience Curriculum Development 12/06 - present
Bart Rypma of the Center for BrainHealth at The University of Texas at Dallas is one of 10 recipients who have been awarded funding from $433,800 in grants from the National Multiple Sclerosis Society.
Rypma’s study uses neuroimaging methods to identify mechanisms involved in MS-related cognitive dysfunction, according to UT Dallas. The society said the 10 high-risk pilot projects are part of the year-long Pilot Research Grant program which supports early-stage research projects to quickly evaluate their effectiveness.
In a recent study, researchers at UT Dallas’ Center for BrainHealth, working in collaboration with colleagues in Sweden, have revealed a link between the dopamine neurotransmitter system in the brain and an individual’s ability to recognize faces. Led by Dr. Bart Rypma, Meadows Foundation Chair in the School of Behavioral and Brain Sciences, the study found that the amount of dopamine relative to the amount of brain activity in the fusiform gyrus strongly predicted the ability to recognize faces. Although the fusiform gyrus has been previously established as an area of the brain related to facial recognition, this is the first time scientists have made a connection between dopamine and facial recognition.
A new study from the Center for BrainHealth at UT Dallas has found how damaging depression can be to a person’s memory and concentration.
In research published in the Journal of Affective Disorders, scientists discovered that depressive thoughts stay with people with depressed moods longer than those without negative thoughts.
“People with depression or even healthy people with a depressed mood can be affected by depressive thoughts,” said Center for BrainHealth principal investigator Dr. Bart Rypma, Meadows Foundation Chair and associate professor in the School of Behavioral and Brain Sciences.
A new way of looking at the brains of multiple sclerosis (MS) patients could greatly enhance doctors’ ability to select the best therapy for each person.
Researchers from The University of Texas at Dallas’ Center for BrainHealth have joined colleagues at UT Southwestern Medical Center to study 3D images of MS lesions in the brain, with the aim of learning to differentiate between injuries that are likely to heal and those that are not.
In a study published online May 30 in the Journal of Neuroimaging, the researchers examined 109 brain lesions from 23 MS patients using a patent-pending technique employing 3 Tesla MRI.
Affiliations
Advisement
Post-doctoral
Michael A. Motes 6/06-present
Dr. Motes is engaged in several projects related to my currently funded NIH and VA grants. Prior to coming to my lab his principal experience was in behavioral research related to spatial cognition. In my lab, Dr. Motes is leaming to combine the methods of experimental psychology with those of neuroimaging (specifically fMRI). Currently, we are exploring the physiology that leads to age-related differences in MRI signal, as well as the neural correlates of age-related changes in working memory.
Joamra Hutchison 8/07 - present
Dr. Hutchison is a new PhD from TCU where she completed her dissertation on problems of visual and auditory boundary extension. In my lab, she is continuing work that follows up her dissertation study and begirming to explore the fundamentals of functional neuroimaging. Together we are formulating a program of research that will allow her to apply the fMRI techniques she learns in my lab with her own interests in spatial and auditory processing.
Michael D. Patterson 5/02 - 5/05
Now on faculty at Nanyang Technical University, Hong Kong
Doctoral
Raj Byrapureddy 8/07 - present
Mr. Byrapureddy has recently arrive in my lab. He previously worked in Dr. Marco Atzori's lab investigating modulation of neuronal firing by neurotransmitters. In my lab, he is starting the process of learning fMRI techniques. As human systems neuroscience is a new enterprise for him, he has been studying basics of neuroimaging and cognition with a concentration on visuospatial working memory. To get hands-on experience, he has been assisting Drs. Motes and Hutchison in their behavioral and neuroimaging studies.
Masters
Liliana Garland 3/07 - present
Liliana has been working in my lab assisting in fMRI and behavioral data collection. Up to the point that she joined my lab her exposure to behavioral neuroscience was limited to the classroom. ln my lab, she is gaining experience with the fundamentals of actual data collection, data analysis and presentation.
Bachelors honors
Eric Zaccone (Rutgers)
Currently enrolled in Neuroscience Doctoral Program, West Virginia University
Funding
Attention and executive ftmction in the cortical and subcortical circuitry of Gulf War Veterans
$770,414 - United States Veteran's Administration [2007–2011]
Aging of working memory: Biophysical, neural, and cognitive components
$1,450,000 - National Institutes of Health [2007–2011]
A pattem-based analysis of neural mediators of working memory deficits in autism
$100,000 - University of Texas at Dallas/University of Texas Southwestem Medical Center Grant [2007–2008]