Bart Rypma

Meadows Foundation Chair in Behavioral Brain Sciences
Professor - Behavioral and Brain Sciences
Tags: Cognition and Neuroscience

Professional Preparation

Ph.D. - Psychology
Georgia Institute of Technology - 1994
M.A. - Psychology
Duke University - 1989
B.A. - Psychology
New York University - 1983

Publications

Di, X., Kannurpatti, S.S., Rypma, B. and Biswal, B.B. (2012). Calibrating BOLD fMRI activation with neurovascular and anatomical constraints. Cerebral Cortex, in press. 2012 - Publication
Hutchison, J.L., Hubbard, T.L., Ferrandino, B., Brigante, R., Wright, J.M. and Rypma, B. (2012). Auditory memory distortion for spoken prose. Journal of Experimental Psychology: Learning, Memory and Cognition, in press. 2012 - Publication
Hutchison, J.L., Lu, H. and Rypma, B. (2012). Neural mechanisms of age-related slowing: The CBF/CMRO2 ratio mediates age-differences in BOLD signal and human performance. Cerebral Cortex, in press. 2012 - Publication
Kannurpatti, S.S., Rypma, B. and Biswal, B.B. (2012). Prediction of task-related BOLD fMRI with amplitude signatures of resting-state fMRI. Frontiers in Systems Neuroscience, 6:7. 2012 - Publication
Shokri-Kojori, E., Motes, M., Rypma, B. and Krawczyk, D. (2012). The network architecture of cortical processing in visuo-spatial reasoning. Nature Scientific Reports, 2, 411. 2012 - Publication
Bennett, I.J., Motes, M.A., Rao, N.K. and Rypma, B. (2012). Relationships between white matter integrity and visual search in healthy aging. Neurobiology of Aging, 33, 433.e21-e31. 2012 - Publication
Lu, H., Hutchison, J., Xu, F. and Rypma, B. (2011). The relationship between M in calibrated fMRI and the physiologic modulators of fMRI. Open Neuroimage Journal. 2011 - Publication
Kannurpatti, S.S., Motes, M.A., Rypma, B. and Biswal, B.B. (2011). Hypercapnic scalability of the fMRI-BOLD signal in blocked and event-related design paradigms. Magnetic Resonance Imaging, 29, 140-146. 2011 - Publication
Prabhakaran, V., Rypma B., Narayanan, N.S., Meier, T.B., Austin, B.P., Nair, V.A., Naing, L., Thomas, L.E. and Gabrieli, J.D. (2011). Capacity-speed relationships in prefrontal cortex. PLoS One, 6, e27504. 2011 - Publication
Kannurpatti, S.S., Motes, M.A., Rypma, B. and Biswal, B.B. (2011). Non-neural BOLD variability in block and event-related paradigms. Magnetic Resonance Imaging, 29, 140-146. 2011 - Publication

Appointments

Associate Professor
University of Texas-Southwestern Medical Center [2006–Present]
Associate Professor
The University of Texas at Dallas [2006–Present]
Clinical Assistant Professor
University of Medicine and Dentistry of New Jersey [2001–2006]
Assistant Professor
Rutgers University [2001–2006]
Associate Research Scientist
University of California-Berkeley [2000–2001]
Postdoctoral Research Fellow
University of Pennsylvania [1997–2000]
NRSA Postdoctoral Research Fellow
Stanford University [1994–1997]
Research Assistant
Duke University [1989–1989]
Research Assistant
Georgia Institute of Technology [1989–1994]
Research Associate
New York University Medical Center [1987–1987]

Projects

Isolating neural mechanisms of age-related cognitive change using fMRI.
1999–1999 Rypma, B. (1999). Psychology Dept. Colloquium, University of Delaware, Newark, DE.
Dissociating age-related changes in working memory strategy and efficiency using event-related fMRI.
2004–2004 Rypma, B. (2004).The 2nd International Conference on Working Memory, Kyoto, Japan
Individual differences in working memory: Effects of age and processing speed.
2006–2006 Rypma, B. (2006).Neurology-Psychiatry Grand Rounds, University of Texas-Southwestern Medical Center, Dallas, TX.
The neural mechanisms of mental storage.
2000–2000 Rypma, B. (2000). The neural mechanisms of mental storage. Psychology Dept. Colloquium, San Diego State University, San Diego, CA.
Isolating the neural mechanisms of age-related changes in working memory: Effects of age and individual differences.
2003–2003 Rypma, B. (2003).Symposium on Attention and working memory changes with aging at the Society for Psychophysical Research, Chicago, IL.

Additional Information

Professional recognitions, honors, memberships
  • Busch Biomedical Sciences Research Award, 2005, Rutgers University  
  • Johnson & Johnson Pioneers in Science Award, 2005, Johnson & Johnson
  • Siemens Award for Innovative Techr1ology Research, 2003, Siemens
  • American Federation of Aging Research Award, 1999, American Federation of Aging Research
  • National Research Service Award, 1994, National lnstitute on Aging
  • Georgia Tech Student Foundation Award, 1991, Georgia Tech Student Foundation
  • Psychology Dept. Award for Distinguished Research, 1984, New York University Psychology Dept. .
  • University Honors Scholar, 1983, New York University
  • Citrin Award for Outstanding Honors Thesis, 1983, New York University Psychology Dept.
  • Dean's Outstanding Service Award, 1983, New York University
  • Honors in Psychology, 1983, New York University
  • Deans List, 1982-83, New York University
  • Psychology Dept. Award for Distinguished Research, 1982, New York University Psychology Dept.
  • Society for Neuroscience, 1995
  • Cognitive Neuroscience Society, 1995
  • American Psychological Association, 1994
  • Sigma Xi (Associate), 1994
  • Psi Chi, 1982
Administration and Curricular Development
  • UTD/UTSW Faculty Liaison 9/06-present
  • UTD Human Neuroscience Curriculum Development 12/06 - present

News Articles

UT Dallas Researcher Gets MS Society Grant
Bart Rypma of the Center for BrainHealth at The University of Texas at Dallas is one of 10 recipients who have been awarded funding from $433,800 in grants from the National Multiple Sclerosis Society.

Rypma’s study uses neuroimaging methods to identify mechanisms involved in MS-related cognitive dysfunction, according to UT Dallas. The society said the 10 high-risk pilot projects are part of the year-long Pilot Research Grant program which supports early-stage research projects to quickly evaluate their effectiveness.
BrainHealth Scientists Connect Dopamine, Facial Recognition in Study
In a recent study, researchers at UT Dallas’ Center for BrainHealth, working in collaboration with colleagues in Sweden, have revealed a link between the dopamine neurotransmitter system in the brain and an individual’s ability to recognize faces. 
Led by Dr. Bart Rypma, Meadows Foundation Chair in the School of Behavioral and Brain Sciences, the study found that the amount of dopamine relative to the amount of brain activity in the fusiform gyrus strongly predicted the ability to recognize faces. Although the fusiform gyrus has been previously established as an area of the brain related to facial recognition, this is the first time scientists have made a connection between dopamine and facial recognition.
Study Reveals the Damaging Effects of Depression on Memory, Mind
A new study from the Center for BrainHealth at UT Dallas has found how damaging depression can be to a person’s memory and concentration. 

In research published in the Journal of Affective Disorders, scientists discovered that depressive thoughts stay with people with depressed moods longer than those without negative thoughts.

“People with depression or even healthy people with a depressed mood can be affected by depressive thoughts,” said Center for BrainHealth principal investigator Dr. Bart Rypma, Meadows Foundation Chair and associate professor in the School of Behavioral and Brain Sciences.

Affiliations

Advisement
Post-doctoral Michael A. Motes 6/06-present Dr. Motes is engaged in several projects related to my currently funded NIH and VA grants. Prior to coming to my lab his principal experience was in behavioral research related to spatial cognition. In my lab, Dr. Motes is leaming to combine the methods of experimental psychology with those of neuroimaging (specifically fMRI). Currently, we are exploring the physiology that leads to age-related differences in MRI signal, as well as the neural correlates of age-related changes in working memory. Joamra Hutchison 8/07 - present Dr. Hutchison is a new PhD from TCU where she completed her dissertation on problems of visual and auditory boundary extension. In my lab, she is continuing work that follows up her dissertation study and begirming to explore the fundamentals of functional neuroimaging. Together we are formulating a program of research that will allow her to apply the fMRI techniques she learns in my lab with her own interests in spatial and auditory processing. Michael D. Patterson 5/02 - 5/05 Now on faculty at Nanyang Technical University, Hong Kong Doctoral Raj Byrapureddy 8/07 - present Mr. Byrapureddy has recently arrive in my lab. He previously worked in Dr. Marco Atzori's lab investigating modulation of neuronal firing by neurotransmitters. In my lab, he is starting the process of learning fMRI techniques. As human systems neuroscience is a new enterprise for him, he has been studying basics of neuroimaging and cognition with a concentration on visuospatial working memory. To get hands-on experience, he has been assisting Drs. Motes and Hutchison in their behavioral and neuroimaging studies. Masters Liliana Garland 3/07 - present Liliana has been working in my lab assisting in fMRI and behavioral data collection. Up to the point that she joined my lab her exposure to behavioral neuroscience was limited to the classroom. ln my lab, she is gaining experience with the fundamentals of actual data collection, data analysis and presentation. Bachelors honors Eric Zaccone (Rutgers) Currently enrolled in Neuroscience Doctoral Program, West Virginia University

Funding

Aging of working memory: Biophysical, neural, and cognitive components
$1,450,000 - National Institutes of Health [2007–2011]
Attention and executive ftmction in the cortical and subcortical circuitry of Gulf War Veterans
$770,414 - United States Veteran's Administration [2007–2011]
A pattem-based analysis of neural mediators of working memory deficits in autism
$100,000 - University of Texas at Dallas/University of Texas Southwestem Medical Center Grant [2007–2008]
A psychometric approach to examining fMRI
$2000 - University of Texas at Dallas [2006–2007]
Neural correlates of age-related memory decline
$5,000 - Busch Foundation [2005–2006]